Human pluripotent stem cells have emerged as a promising in vitro model system for
studying the brain. Two-dimensional and three-dimensional cell culture paradigms have …

Stem cell therapy is widely recognized as a promising strategy for exerting therapeutic
effects after injury in degenerative diseases. However, limitations such as low cell retention …

Since the advent of the generation of human induced pluripotent stem cells (hiPSCs),
numerous protocols have been developed to differentiate hiPSCs into cardiomyocytes and …

Basic fibroblast growth factor (FGF)-2 has been shown to regulate many cellular functions
including cell proliferation, migration, and differentiation, as well as angiogenesis in a variety …

Background Induced pluripotent stem cells (iPSCs) offer potential to revolutionize
regenerative medicine as a renewable source for islets, dopaminergic neurons, retinal cells …

Background: Fibroblast growth factor (FGF)–2 has the potential to enhance tendon-to-bone
healing after rotator cuff (RC) injury. Hypothesis: FGF-2 stimulates tenogenic differentiation …

Bone is a metabolically active organ that undergoes continuous remodeling throughout life.
However, many complex skeletal defects such as large traumatic bone defects or extensive …

Background: The effects of fibroblast growth factor 2 (FGF-2) on healing after surgical repair
of chronic rotator cuff (RC) tears remain unclear. Hypothesis: FGF-2 enhances tenogenic …

The poor regenerative capability of stem cell transplantation in the central nervous system
limits their therapeutic efficacy in brain injuries. The sustained inflammatory response, lack …

Abstract Induced Pluripotent Stem Cells (iPSCs) are self renewable and can differentiate to
different types of adult cells, which has shown great promises in the field of regenerative …