Background Digital therapeutics are patient-facing digital health interventions that can
significantly alter the health care landscape. Despite digital therapeutics being used to …

Amyotrophic lateral sclerosis (ALS) is the most common subtype of motor neuron disease
(MND). The current gold-standard measure of progression is the ALS Functional Rating …

Abstract Background The ALS Functional Rating Scale in its revised version (ALSFRS-R) is
a disease-specific severity score that reflects motor impairment and functional deterioration …

Abstract Introduction/Aims In amyotrophic lateral sclerosis (ALS) caused by SOD1 mutations
(SOD1‐ALS), tofersen received accelerated approval in the United States and is available …

Objective Remote self-assessment of the revised amyotrophic lateral sclerosis functional
rating scale (ALSFRS-R) using digital data capture was investigated for its feasibility as an …

Introduction To capture the patient's attitude toward remote monitoring of motor neuron
disease (MND) in care and clinical trials, and their concerns and preferences regarding the …

Alzheimer's disease (AD) and other neurodegenerative diseases such as Parkinson's
disease (PD) and Huntington's disease (HD) are associated with progressive cognitive …

Facioscapulohumeral muscular dystrophy (FSHD) is a debilitating muscular dystrophy with a
variable age of onset, severity, and progression. While there is still no cure for this disease …

Background Actigraphy has been proposed as a measure for tracking functional decline and
disease progression in patients with Motor Neuron Disease (MND). There is, however, little …

Background Home-monitoring of spirometry has the potential to improve care for patients
with a motor neuron disease (MND) by enabling early detection of respiratory dysfunction …