New insights into oxidative stress and inflammatory response in neurodegenerative diseases

E Scarian, C Viola, F Dragoni, R Di Gerlando… - International Journal of …, 2024 - mdpi.com
Oxidative stress (OS) and inflammation are two important and well-studied pathological
hallmarks of neurodegenerative diseases (NDDs). Due to elevated oxygen consumption, the …

[HTML][HTML] Calcium ions in the physiology and pathology of the central nervous system

D Pikor, M Hurła, B Słowikowski… - International Journal of …, 2024 - mdpi.com
Calcium ions play a key role in the physiological processes of the central nervous system.
The intracellular calcium signal, in nerve cells, is part of the neurotransmission mechanism …

What dietary vitamins and minerals might be protective against Parkinson's disease?

M Alizadeh, S Kheirouri, M Keramati - Brain Sciences, 2023 - mdpi.com
Background and Objective: Dietary constituents may affect the progression of Parkinson's
disease (PD). This study aimed to assess the contribution of dietary intake of vitamins and …

The Role of Calcium and Iron Homeostasis in Parkinson's Disease

J Wang, J Zhao, K Zhao, S Wu, X Chen, W Hu - Brain Sciences, 2024 - mdpi.com
Calcium and iron are essential elements that regulate many important processes of
eukaryotic cells. Failure to maintain homeostasis of calcium and iron causes cell dysfunction …

Parkinson's disease etiology: insights and associations with phosphate toxicity

RB Brown - International Journal of Molecular Sciences, 2022 - mdpi.com
The present paper investigated the association of Parkinson's disease etiology with
phosphate toxicity, a pathophysiological condition in which dysregulated phosphate …

The effect of hypocalcemia on motor symptoms of Parkinson's disease

EM Emad, ASE Elmotaym, MA Ghonemy… - The Egyptian Journal of …, 2022 - Springer
Background The disabling nature of Parkinson's disease (PD) impairs functional mobility
and worsens quality of life. Calcium imbalances are thought to have a significant role in the …

Status of circulating bone turnover markers in elderly osteoporosis/osteopenia patients in comparison with healthy subjects

SS Tehrani, M Moallem, R Ebrahimi, SR Hosseini… - Asian …, 2020 - sciendo.com
Background: In the aging individuals, osteoporosis is a major health problem. Due to the
various limitations of dual X-ray absorptiometry (DEXA) for diagnosis osteoporosis, serum …

Amyloid Beta sharply increases HMG-CoA reductase protein levels in astrocytes isolated from C57BL/6 mice

M Cheraghzadeh, Z Nazeri, A Mohammadi… - Gene Reports, 2021 - Elsevier
Introduction It is believed that the accumulation of Amyloid Beta (Aβ) and brain cholesterol
are involved in Alzheimer's pathophysiology. Consequently, regulation of brain cholesterol …

[PDF][PDF] TRPing the calcium homeostasis in Parkinson's disease

I Saeed, B Garland, L Ma - Cell Signal, 2023 - probiologists.com
Parkinson's Disease (PD) is a neurological disorder characterized by the loss of
dopaminergic neurons in the substantia nigra pars compacta (SNpc) region of the midbrain …

A novel highly-sensitive assay for the analysis of cerebrospinal fluid and blood Visinin-like protein 1 in Alzheimer's and other neurodegenerative diseases

D Riedel - 2024 - oparu.uni-ulm.de
Alzheimer's disease (AD) is a neurodegenerative disease whose pathology is estimated to
begin several years prior to the onset of clinical features. However, clinical symptoms occur …