Copper active sites in biology

EI Solomon, DE Heppner, EM Johnston… - Chemical …, 2014 - ACS Publications
On the basis of its generally accessible I/II redox couple and bioavailability, copper plays a
wide variety of roles in nature that mostly involve electron transfer (ET), O 2 binding …

Proton-coupled electron transfer in cytochrome oxidase

VRI Kaila, MI Verkhovsky, M Wikström - Chemical reviews, 2010 - ACS Publications
Enzyme reactions that involve strong coupling between proton and electron transfer are of
fundamental importance in biology. This is particularly evident in the reactions of primary …

New perspectives on proton pumping in cellular respiration

M Wikstrom, V Sharma, VRI Kaila, JP Hosler… - Chemical …, 2015 - ACS Publications
Cellular respiration has a long research history at the interface between biology, chemistry,
and physics. Research in this field spans the entire range from fundamental mechanistic and …

[HTML][HTML] Et tu, Grotthuss! and other unfinished stories

S Cukierman - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2006 - Elsevier
This review article is divided into three sections. In Section 1, a short biographical note on
Freiherr von Grotthuss is followed by a detailed summary of the main findings and ideas …

Voltage-gated proton channels and other proton transfer pathways

TE Decoursey - Physiological reviews, 2003 - journals.physiology.org
Proton channels exist in a wide variety of membrane proteins where they transport protons
rapidly and efficiently. Usually the proton pathway is formed mainly by water molecules …

The oxidative phosphorylation system in mammalian mitochondria

S Papa, PL Martino, G Capitanio, A Gaballo… - Advances in …, 2012 - Springer
The chapter provides a review of the state of art of the oxidative phosphorylation system in
mammalian mitochondria. The sections of the paper deal with:(i) the respiratory chain as a …

The X-ray crystal structures of wild-type and EQ (I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides

M Svensson-Ek, J Abramson, G Larsson… - Journal of molecular …, 2002 - Elsevier
The structure of cytochrome c oxidase from Rhodobacter sphaeroides has been solved at
2.3/2.8 Å (anisotropic resolution). This high-resolution structure revealed atomic details of a …

Time-resolved serial crystallography to track the dynamics of carbon monoxide in the active site of cytochrome c oxidase

C Safari, S Ghosh, R Andersson, J Johannesson… - Science …, 2023 - science.org
Cytochrome c oxidase (C c O) is part of the respiratory chain and contributes to the
electrochemical membrane gradient in mitochondria as well as in many bacteria, as it uses …

Energy transduction: proton transfer through the respiratory complexes

JP Hosler, S Ferguson-Miller, DA Mills - Annu. Rev. Biochem., 2006 - annualreviews.org
A series of metalloprotein complexes embedded in a mitochondrial or bacterial membrane
utilize electron transfer reactions to pump protons across the membrane and create an …

A mechanistic principle for proton pumping by cytochrome c oxidase

K Faxén, G Gilderson, P Ädelroth, P Brzezinski - Nature, 2005 - nature.com
In aerobic organisms, cellular respiration involves electron transfer to oxygen through a
series of membrane-bound protein complexes. The process maintains a transmembrane …