Antiviral and antimicrobial applications of chalcones and their derivatives: From nature to greener synthesis

MH Nematollahi, M Mehrabani, Y Hozhabri… - Heliyon, 2023 - cell.com
Chalcones and their derivatives have been widely studied due to their versatile
pharmacological and biological activities, such as anti-inflammatory, antibacterial, antiviral …

Biogenic synthesis, characterization, antimicrobial, antioxidant, antidiabetic, and catalytic applications of platinum nanoparticles synthesized from Polygonum …

M Hosny, M Fawzy, EM El-Fakharany, AM Omer… - Journal of …, 2022 - Elsevier
The aqueous extract of P. salicifolium leaves was employed in the green synthesis of
platinum nanoparticles (PS-PtNPs) by an immediate, one step, cost-effective procedure in …

An Update on Phytochemicals and Pharmacological Activities of the Genus Persicaria and Polygonum

G Seimandi, N Álvarez, MI Stegmayer, L Fernández… - Molecules, 2021 - mdpi.com
The discovery of new pharmaceutical identities, particularly anti-infective agents, represents
an urgent need due to the increase in immunocompromised patients and the …

Antimicrobial activity of some plant extracts and their applications in homemade tomato paste and pasteurized cow milk as natural preservatives

ESH Atwaa, MR Shahein, HA Radwan, NS Mohammed… - Fermentation, 2022 - mdpi.com
Synthetic chemical preservatives are widely used in the food industry to delay the
deterioration caused by microbial growth, enzyme activities and oxidation reactions. The last …

[HTML][HTML] Thiosugar naphthalene diimide conjugates: G-quadruplex ligands with antiparasitic and anticancer activity

E Belmonte-Reche, A Benassi, P Peñalver… - European Journal of …, 2022 - Elsevier
Glycosyl conjugation to drugs is a strategy being used to take advantage of glucose
transporters (GLUT) overexpression in cancer cells in comparison with non-cancerous cells …

Multienzymatic biotransformation of flavokawain B by entomopathogenic filamentous fungi: structural modifications and pharmacological predictions

P Chlipała, T Tronina, M Dymarska, M Urbaniak… - Microbial Cell …, 2024 - Springer
Background Flavokawain B is one of the naturally occurring chalcones in the kava plant
(Piper methysticum). It exhibits anticancer, anti-inflammatory and antimalarial properties …

Quantum mechanical, molecular docking, molecular dynamics, ADMET and antiproliferative activity on Trypanosoma cruzi (Y strain) of chalcone (E)-1-(2-hydroxy-3, 4 …

MGC Matos, LP da Silva, FWQ Almeida-Neto… - Physical Chemistry …, 2022 - pubs.rsc.org
Chagas disease is a leading public health problem. More than 8 million people are affected
by the disease, which is endemic in 21 countries in Latin America, generating an average …

Trypanocidal potential of synthetic p-aminochalcones: In silico and in vitro evaluation

NDB Gomes, EP Magalhães, LR Ribeiro… - Bioorganic …, 2023 - Elsevier
Chagas disease (CD) is a neglected tropical disease of worldwide health concern, caused
by the flagellate protozoan Trypanosoma cruzi (T. cruzi), endemic in Latin America and …

Allylpolyalkoxybenzene Inhibitors of Galactonolactone Oxidase from Trypanosoma cruzi

AA Chudin, ID Zlotnikov, SS Krylov, VV Semenov… - Biochemistry …, 2023 - Springer
Inhibition of biosynthetic pathways of compounds essential for Trypanosoma cruzi is
considered as one of the possible action mechanisms of drugs against Chagas disease …

Two new dimethylpyranoflavanones from the roots of Melodorum fruticosum

HTM Nguyen, PKP Nguyen, DTT Ngo… - Natural Product …, 2024 - Taylor & Francis
Two previously unreported dimethylpyranoflavanones, pyronomelodorones A and B (1 and
2), along with five known compounds, 7-O-methyldihydrowogonin (3), 5, 6, 7 …