Precise plant genome editing using base editors and prime editors

KA Molla, S Sretenovic, KC Bansal, Y Qi - Nature Plants, 2021 - nature.com
The development of CRISPR–Cas systems has sparked a genome editing revolution in
plant genetics and breeding. These sequence-specific RNA-guided nucleases can induce …

cis-Regulatory Elements in Plant Development, Adaptation, and Evolution

AP Marand, AL Eveland, K Kaufmann… - Annual review of …, 2023 - annualreviews.org
cis-Regulatory elements encode the genomic blueprints that ensure the proper
spatiotemporal patterning of gene expression necessary for appropriate development and …

Targeting a gene regulatory element enhances rice grain yield by decoupling panicle number and size

X Song, X Meng, H Guo, Q Cheng, Y Jing… - Nature …, 2022 - nature.com
Crop genetic improvement requires balancing complex tradeoffs caused by gene pleiotropy
and linkage drags, as exemplified by IPA1 (Ideal Plant Architecture 1), a typical pleiotropic …

An efficient CRISPR–Cas12a promoter editing system for crop improvement

J Zhou, G Liu, Y Zhao, R Zhang, X Tang, L Li, X Jia… - Nature Plants, 2023 - nature.com
Promoter editing represents an innovative approach to introduce quantitative trait variation
(QTV) in crops. However, an efficient promoter editing system for QTV needs to be …

Cis-regulatory sequences in plants: their importance, discovery, and future challenges

RJ Schmitz, E Grotewold, M Stam - The plant cell, 2022 - academic.oup.com
The identification and characterization of cis-regulatory DNA sequences and how they
function to coordinate responses to developmental and environmental cues is of paramount …

New insights into tissue culture plant-regeneration mechanisms

Y Long, Y Yang, G Pan, Y Shen - Frontiers in plant science, 2022 - frontiersin.org
Plant regeneration occurs when plants repair or replace damaged structures based on the
totipotency and pluripotency of their cells. Tissue culture is one of the most widely used …

A cis-regulatory atlas in maize at single-cell resolution

AP Marand, Z Chen, A Gallavotti, RJ Schmitz - Cell, 2021 - cell.com
Summary cis-regulatory elements (CREs) encode the genomic blueprints of spatiotemporal
gene expression programs enabling highly specialized cell functions. Using single-cell …

Variation in cis-regulation of a NAC transcription factor contributes to drought tolerance in wheat

H Mao, S Li, B Chen, C Jian, F Mei, Y Zhang, F Li… - Molecular Plant, 2022 - cell.com
Drought is a major environmental factor limiting wheat production worldwide, and
developing drought-tolerant cultivars is a central challenge for wheat breeders globally …

The integrated genomics of crop domestication and breeding

X Huang, S Huang, B Han, J Li - Cell, 2022 - cell.com
As a major event in human civilization, wild plants were successfully domesticated to be
crops, largely owing to continuing artificial selection. Here, we summarize new discoveries …

A critical review: recent advancements in the use of CRISPR/Cas9 technology to enhance crops and alleviate global food crises

A Rasheed, RA Gill, MU Hassan, A Mahmood… - Current Issues in …, 2021 - mdpi.com
Genome editing (GE) has revolutionized the biological sciences by creating a novel
approach for manipulating the genomes of living organisms. Many tools have been …