Omega is a polyunsaturated fatty acid (PUFA) that has an essential impact on cognitive
performance at all stages of life. Eicosapentaenoic acid (EPA), docosahexaenoic acid …

Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian
cells. PE comprises about 15–25% of the total lipid in mammalian cells; it is enriched in the …

The E4 allele of the apolipoprotein E gene (APOE) has been established as a genetic risk
factor for many diseases including cardiovascular diseases and Alzheimer's disease (AD) …

Many clinical and animal studies demonstrate the importance of long-chain polyunsaturated
fatty acids (LCPUFA) in neural development and neurodegeneration. This review will focus …

Choline is an essential nutrient, but is also formed by de novo synthesis. Choline and its
derivatives serve as components of structural lipoproteins, blood and membrane lipids, and …

Parkinson's disease (PD) is usually characterized by cardinal motor impairments. However,
a range of non-motor symptoms precede the motor-phase and are major determinants for …

Souvenaid aims to improve synapse formation and function. An earlier study in patients with
Alzheimer's disease (AD) showed that Souvenaid increased memory performance after 12 …

Background Ageing is a highly complex process marked by a temporal cascade of events,
which promote alterations in the normal functioning of an individual organism. The triggers …

As people age they become increasingly susceptible to chronic and extremely debilitating
brain diseases. The precise cause of the neuronal degeneration underlying these disorders …

In the last decade, it has become obvious that Alzheimer's disease (AD) is closely linked to
changes in lipids or lipid metabolism. One of the main pathological hallmarks of AD is …