The human menopause transition and aging are each associated with an increase in a
variety of health risk factors including, but not limited to, cardiovascular disease …

More than 5 million Americans are living with Alzheimer's disease (AD) today, and nearly
two-thirds of Americans with AD are women. This sex difference may be due to the higher …

Context: Low testosterone levels in men have been associated with increased mortality.
However, the influence of testosterone treatment on mortality in men with low testosterone …

Estrogens play a crucial physiological function in the brain; however, debates exist
concerning the role of estrogens in Alzheimer's disease (AD). Women during pre-, peri-, or …

Sex differences in neurological disease extend from incidence, severity, progression and
symptoms and may ultimately influence treatment. Cognitive disturbances are frequent in …

This article is part of a Special Issue “Estradiol and Cognition”. There are sex differences in
hippocampus-dependent cognition and neurogenesis suggesting that sex hormones are …

Importance Postmenopausal hormone therapy with conjugated equine estrogens (CEEs)
may adversely affect older women's cognitive function. It is not known whether this extends …

17β-Estradiol (estradiol or E2) is implicated as a neuroprotective factor in a variety of
neurodegenerative disorders. This review focuses on the mechanisms underlying E2 …

Menopause in human females and subsequent ovarian hormone deficiency, particularly
concerning 17β-estradiol (E2), increase the risk for metabolic dysfunctions associated with …

This article is part of a Special Issue “Estradiol and cognition”. Estrogens are becoming well
known for their robust enhancement on cognition particularly for learning and memory that …