Breast cancer is the most malignant tumor in women, and there is no absolute cure for it.
Although treatment modalities including surgery, chemotherapy, and radiotherapy are …

Lung cancer is the leading cause of cancer-related mortality worldwide. Although the
PI3K/Akt/mTOR signaling pathway has recently been considered as one of the most altered …

Pyroptosis is a highly inflammatory programmed cell death that activates inflammatory
response, reverses immunosuppression and promotes systemic immune response for solid …

The burden of cancer is increasing globally. Several challenges facing its mainstream
treatment approaches have formed the basis for the development of targeted delivery …

Oral cavity carcinomas are the most frequent malignancies among head and neck
malignancies. Oral tumors include not only oral cancer cells with different potency and …

The functional concept of using synthetic entities to supplement or replace certain functions
or structures of biological cells is realized by the development of atypical artificial cells using …

Cancer immunotherapy is developing as the mainstream strategy for treatment of cancer.
However, the interaction between the programmed cell death protein-1 (PD-1) and the …

Nowadays, breast cancer has become the most common cancer worldwide with a high
mortality rate. Immune checkpoint blockade holds great promise in tumor‐targeted therapy …

Breast cancer (BC), the most common cancer in women, is caused by the uncontrolled
proliferation of mammary epithelial cells under the action of a variety of carcinogenic factors …

Background Local tumor microenvironment (TME) plays a crucial role in immunotherapy for
breast cancer (BC). Whereas, the molecular mechanism responsible for the crosstalk …