[HTML][HTML] Glucosinolate structural diversity, identification, chemical synthesis and metabolism in plants

I Blažević, S Montaut, F Burčul, CE Olsen, M Burow… - Phytochemistry, 2020 - Elsevier
The glucosinolates (GSLs) is a well-defined group of plant metabolites characterized by
having an S-β-d-glucopyrano unit anomerically connected to an O-sulfated (Z) …

Molecular targets of isothiocyanates in cancer: recent advances

P Gupta, B Kim, SH Kim… - Molecular nutrition & food …, 2014 - Wiley Online Library
Cancer is a multistep process resulting in uncontrolled cell division. It results from aberrant
signaling pathways that lead to uninhibited cell division and growth. Various recent …

The recent advances of glucosinolates and their metabolites: Metabolism, physiological functions and potential application strategies

J Wu, S Cui, J Liu, X Tang, J Zhao… - Critical reviews in …, 2023 - Taylor & Francis
Glucosinolates and their metabolites from Brassicaceae plants have received widespread
attention due to their anti-inflammatory effects. Glucosinolates occurs an “enterohepatic …

Assessment of methodological pipelines for the determination of isothiocyanates derived from natural sources

S Kyriakou, DT Trafalis, MV Deligiorgi, R Franco… - Antioxidants, 2022 - mdpi.com
Isothiocyanates are biologically active secondary metabolites liberated via enzymatic
hydrolysis of their sulfur enriched precursors, glucosinolates, upon tissue plant disruption …

Mechanisms of the anticancer effects of isothiocyanates

NM Fofaria, A Ranjan, SH Kim, SK Srivastava - The enzymes, 2015 - Elsevier
Cancer results from aberrant signaling pathways that result in uncontrolled cellular
proliferation. The epidemiological studies have shown a strong inverse correlation between …

Glucosinolate hydrolysis products in the crucifer Barbarea vulgaris include a thiazolidine-2-one from a specific phenolic isomer as well as oxazolidine-2-thiones

N Agerbirk, CE Olsen - Phytochemistry, 2015 - Elsevier
Two isomeric phenolic glucosinolates, m-and p-hydroxyl derivatives of epiglucobarbarin [(R)-
2-hydroxy-2-phenylethylglucosinolate], co-occur in an eastern chemotype (P-type) of the …

Isothiocyanates as Tubulin Polymerization Inhibitors—Synthesis and Structure–Activity Relationship Studies

R Grzywa, M Psurski, A Gajda, T Gajda… - International Journal of …, 2023 - mdpi.com
Among the various substances that interfere with the microtubule formation process,
isothiocyanates (ITCs) are the group of compounds for which the binding mode and …

The comparison of cytotoxic and genotoxic activities of glucosinolates, isothiocyanates, and indoles

D Kołodziejski, I Koss-Mikołajczyk, H Glatt… - Scientific reports, 2022 - nature.com
Chemopreventive properties of Brassica vegetables are attributed mainly to their
characteristic compounds—glucosinolates (GLs) and their main hydrolysis products …

Glucosinolate-derived isothiocyanates inhibit Arabidopsis growth and the potency depends on their side chain structure

J Urbancsok, AM Bones, R Kissen - International Journal of Molecular …, 2017 - mdpi.com
Isothiocyanates (ITCs), the biologically important glucosinolate breakdown products, can
present health-promoting effects, play an important role in plant defense and affect plant …

[HTML][HTML] Glucosinolate catabolism during postharvest drying determines the ratio of bioactive macamides to deaminated benzenoids in Lepidium meyenii (maca) root …

E Esparza, W Yi, F Limonchi, EG Cosio - Phytochemistry, 2020 - Elsevier
Postharvest processing of maca (Lepidium meyenii Walp., Brassicaceae), a traditional high-
altitude Andean root crop, involves slow field drying prior to milling into flour. The …