The daily alternation between sleep and wakefulness is one of the most dominant features
of our lives and is a manifestation of the intrinsic 24 h rhythmicity underlying almost every …

Circadian disruption is pervasive and can occur at multiple organizational levels,
contributing to poor health outcomes at individual and population levels. Evidence points to …

Caloric restriction (CR) prolongs life span, yet the mechanisms by which it does so remain
poorly understood. Under CR, mice self-impose chronic cycles of 2-hour feeding and 22 …

Sleep is entwined across many physiologic processes in the brain and periphery, thereby
exerting tremendous influence on our well-being. Yet sleep exists in a social-environmental …

Circadian rhythms evolved through adaptation to daily light/dark changes in the
environment; they are believed to be regulated by the core circadian clock interlocking …

The circadian rhythm is an evolutionarily conserved time-keeping system that comprises a
wide variety of processes including sleep–wake cycles, eating–fasting cycles, and activity …

Background Light has powerful effects on mood, sleep, and the circadian system. Humans
evolved in an environment with a clear distinction between day and night, but our modern …

Physical endurance and energy conservation are essential for survival in the wild. However,
it remains unknown whether and how meal timing regulates physical endurance and muscle …

Background Daily rhythms are observed in humans and almost all other organisms. Most of
these observed rhythms reflect both underlying endogenous circadian rhythms and evoked …

Personalization of ICU nutrition is essential to future of critical care. Recommendations from
American/European guidelines and practice suggestions incorporating recent literature are …