The regulation of spermatogenesis by androgens

LB Smith, WH Walker - Seminars in cell & developmental biology, 2014 - Elsevier
Testosterone is essential for maintaining spermatogenesis and male fertility. However, the
molecular mechanisms by which testosterone acts have not begun to be revealed until …

Neuroendocrine control of the onset of puberty

TM Plant - Frontiers in neuroendocrinology, 2015 - Elsevier
This chapter is based on the Geoffrey Harris Memorial Lecture presented at the 8th
International Congress of Neuroendocrinology, which was held in Sydney, August 2014. It …

Factors affecting spermatogenesis upon gonadotropin‐replacement therapy: a meta‐analytic study

G Rastrelli, G Corona, E Mannucci, M Maggi - Andrology, 2014 - Wiley Online Library
A meta‐analysis was performed to systematically analyse the results of gonadotropin and
GnRH therapy in inducing spermatogenesis in subjects with hypogonadotropic …

Androgen actions in the testis and the regulation of spermatogenesis

WH Walker - Molecular Mechanisms in Spermatogenesis, 2021 - Springer
Testosterone is essential for spermatogenesis and male fertility. In this review, topics related
to testosterone control of spermatogenesis are covered including testosterone production …

The molecular mechanism of sex hormones on Sertoli cell development and proliferation

W Shah, R Khan, B Shah, A Khan, S Dil… - Frontiers in …, 2021 - frontiersin.org
Sustaining and maintaining the intricate process of spermatogenesis is liable upon
hormones and growth factors acting through endocrine and paracrine pathways. The Sertoli …

The role of GnRH in Tibetan male sheep and goat reproduction

W Zhao, M Adjei, Z Zhang, Z Yuan… - … in Domestic Animals, 2023 - Wiley Online Library
The hypothalamic‐pituitary‐gonadal (HPG) axis connects the hypothalamus, pituitary gland,
and gonads. The regulation of reproductive processes includes integrating various factors …

Understanding testicular single cell transcriptional atlas: from developmental complications to male infertility

MB Tirumalasetty, I Bhattacharya… - Frontiers in …, 2024 - frontiersin.org
Spermatogenesis is a multi-step biological process where mitotically active diploid (2n)
spermatogonia differentiate into haploid (n) spermatozoa via regulated meiotic …

Etiology of male infertility: an update

I Bhattacharya, SS Sharma, SS Majumdar - Reproductive Sciences, 2024 - Springer
Spermatogenesis is a complex process of germ cell division and differentiation that involves
extensive cross-talk between the developing germ cells and the somatic testicular cells …

Application of three-dimensional culture systems to study mammalian spermatogenesis, with an emphasis on the rhesus monkey (Macaca mulatta)

M Huleihel, S Nourashrafeddin… - Asian journal of …, 2015 - journals.lww.com
In vitro culture of spermatogonial stem cells (SSCs) has generally been performed using two-
dimensional (2D) culture systems; however, such cultures have not led to the development …

FSH for the Treatment of Male Infertility

L Casarini, P Crépieux, E Reiter, C Lazzaretti… - International journal of …, 2020 - mdpi.com
Follicle-stimulating hormone (FSH) supports spermatogenesis acting via its receptor
(FSHR), which activates trophic effects in gonadal Sertoli cells. These pathways are targeted …