Efficient and targeted delivery of a DNA payload is vital for developing safe gene therapy.
Owing to the recent success of commercial oncolytic vector and multiple COVID-19 …

Since its initial characterization in 2016, the interferon stimulated gene Shiftless (SHFL) has
proven to be a critical piece of the innate immune response to viral infection. SHFL …

Adenoviral vectors, both oncolytic viruses and gene delivery vectors, are among the earliest
approved and commercialised vectors for gene therapy. Adenoviruses have high cytotoxicity …

Simple Summary Bladder cancer is a common disease in urological patients. The approach
to treatment depends on the severity of the tumor; in this article, we focus on tumors that do …

Bladder cancer (BLCA) is featured with high incidence and mortality. Whether the IFN-γ
signaling could be used as an immunotherapy determinant for BLCA has not been fully …

Abstract Bacillus Calmette-Guérin (BCG) treatment for non-muscle invasive bladder cancer
(NMIBC) is an established immunotherapeutic, however, a significant portion of patients do …

Effective bladder-preserving therapeutic options are needed for patients with bacillus
Calmette-Guérin unresponsive non–muscle-invasive bladder cancer. Nadofaragene …

As the amount of available data continues to grow in fields as diverse as bioinformatics,
physics, and remote sensing, the importance of scientific workflows in the design and im …

Non-muscle-invasive bladder cancer (NMIBC), which is restricted to the mucosa (stage Ta,
carcinoma in situ (CIS)) or submucosa (stage T1), comprises 75% of bladder cancer …

Scientific workflows are used to analyze large amounts of data. These workflows comprise
numerous tasks, many of which are executed repeatedly, running the same custom program …