The nuclear factor kappa B (NF-κB) pathway has emerged as a pivotal player in the
pathogenesis of various diseases, including neurodegenerative illnesses like Alzheimer's …

Gliomas are a diverse group of primary central nervous system neoplasms with no curative
therapies available. Brain macrophages comprise microglia in the brain parenchyma, border …

Cancer is daunting pathology with remarkable breadth and scope, spanning genetics,
epigenetics, proteomics, metalobomics and cell biology. Cellular senescence represents a …

The NLRP3 inflammasome represents a cytoplasmic multiprotein complex with the
capability to recognize a wide range of pathogen-derived, environmental, and endogenous …

Alzheimer's disease (AD), a central cause of dementia, is characterized by the accumulation
of amyloid β-peptide (Aβ) peptides in the brain. P-glycoprotein (P-gp), a highly expressed …

Bruguiera gymnorhiza is a mangrove plant that contains many bioactive compounds, which
exhibit anti-inflammatory properties. This study aims to evaluate the anti-inflammatory …

Background: Pneumococcal infection of the central nervous system generates a massive
inflammatory reaction which can cause brain damage and thus contributes to unfavourable …