Heart–brain interactions in cardiac and brain diseases: why sex matters

A Rossi, N Mikail, S Bengs, A Haider… - European heart …, 2022 - academic.oup.com
Cardiovascular disease and brain disorders, such as depression and cognitive dysfunction,
are highly prevalent conditions and are among the leading causes limiting patient's quality …

New insights into sympathetic regulation of glucose and fat metabolism

K Nonogaki - Diabetologia, 2000 - Springer
The autonomic nervous system modulates glucose and fat metabolism through both direct
neural effects and hormonal effects. This review presents recent concepts on the …

Gender, sex hormones and autonomic nervous control of the cardiovascular system

AM Dart, XJ Du, BA Kingwell - Cardiovascular research, 2002 - academic.oup.com
1. Introduction Differences in the autonomic system may be due to differences in afferent
receptor stimulation, in central The autonomic nervous system is of importance in the reflex …

Sex differences in the development of angiotensin II-induced hypertension in conscious mice

B Xue, J Pamidimukkala, M Hay - American Journal of …, 2005 - journals.physiology.org
Sex has an important influence on blood pressure (BP) regulation. There is increasing
evidence that sex hormones interfere with the renin-angiotensin system. Thus the purpose of …

[HTML][HTML] Estrogen receptor-α mediates estrogen protection from angiotensin II-induced hypertension in conscious female mice

B Xue, J Pamidimukkala… - American Journal of …, 2007 - journals.physiology.org
It has been shown that the female sex hormones have a protective role in the development
of angiotensin II (ANG II)-induced hypertension. The present study tested the hypotheses …

[HTML][HTML] Influence of age and estradiol on sympathetic nerve activity responses to exercise in women

MM Wenner, JL Greaney, EL Matthews… - Medicine and science …, 2022 - ncbi.nlm.nih.gov
Methods. Herein, we tested the hypothesis that sympathetic responses during exercise are
augmented in PMW compared to young women (YW), and estradiol administration …

Autonomic and cardiovascular reflex responses to central estrogen injection in ovariectomized female rats

MC Saleh, BJ Connell, TM Saleh - Brain research, 2000 - Elsevier
The role of estrogen in central autonomic nuclei was examined in ovariectomized female
Sprague–Dawley rats supplemented daily for 7 days with either estrogen (5 μg/kg; sc) or …

Protective effects of estrogen against cardiovascular disease mediated via oxidative stress in the brain

CJ Lagranha, TLA Silva, SCA Silva, GRF Braz… - Life sciences, 2018 - Elsevier
During their reproductive years women produce significant levels of estrogens,
predominantly in the form of estradiol, that are thought to play an important role in …

Sex differences in dementia

E Hogervorst, S Temple, E O'Donnell - Sex differences in brain function …, 2023 - Springer
Background Women in many cohorts have a higher risk for Alzheimer's disease (AD), the
most common form of dementia. Sex is a biological construct whereby differences in disease …

Influence of menstrual cycle on baroreflex control of heart rate: comparison with male volunteers

M Tanaka, M Sato, S Umehara… - American Journal of …, 2003 - journals.physiology.org
This study was designed to determine baroreflex control of heart rate (HR) to hypotensive
and hypertensive stimuli during the early follicular (EF), preovulation (PreOV), and midluteal …