Retinal ganglion cell (RGC) death in glaucoma and other optic neuropathies results in
irreversible vision loss due to the mammalian central nervous system's limited regenerative …

Animal colour vision is based on comparing signals from different photoreceptors. It is
generally assumed that processing different spectral types of photoreceptor mainly serves …

The basic plan of the retina is conserved across vertebrates, yet species differ profoundly in
their visual needs. Retinal cell types may have evolved to accommodate these varied needs …

Optokinetic nystagmus (OKN) assists stabilization of the retinal image during head rotation.
OKN is driven by ON direction selective retinal ganglion cells (ON DSGCs), which encode …

The process wherein dividing cells exhaust proliferative capacity and enter into replicative
senescence has become a prominent model for cellular aging in vitro. Despite decades of …

Retinal ganglion cells (RGCs) are the brain's gateway to the visual world. They can be
classified into different types on the basis of their electrophysiological, transcriptomic, or …

From mouse to primate, there is a striking discontinuity in our current understanding of the
neural coding of motion direction. In non-primate mammals, directionally selective cell types …

The genesis of broad neuronal classes from multipotential neural progenitor cells has been
extensively studied, but less is known about the diversification of a single neuronal class into …

Neovascular age-related macular degeneration (nAMD) is the leading cause of blindness in
the developed world. Current therapy includes monthly intraocular injections of anti-VEGF …

A retinal prosthesis, also known as a bionic eye, is a device that can be implanted to partially
restore vision in patients with retinal diseases that have resulted in the loss of …