Evolution of Drug-Resistant Mycobacterium tuberculosis Strains and Their Adaptation to the Human Lung Environment

A Allué-Guardia, JI García, JB Torrelles - Frontiers in Microbiology, 2021 - frontiersin.org
In the last two decades, multi (MDR), extensively (XDR), extremely (XXDR) and total (TDR)
drug-resistant Mycobacterium tuberculosis (M. tb) strains have emerged as a threat to public …

Nocardia seriolae mediates liver granulomatous chronic inflammation in Micropterus salmoides through pyroptosis

ZY Zhou, SJ Bai, CW Lu, B Yang, J Wang… - Journal of Fish …, 2023 - Wiley Online Library
Granulomatous diseases caused by Nocardia seriously endanger the health of cultured fish.
These bacteria are widely distributed, but prevention and treatment methods are very …

TB or not to be: what specificities and impact do antibodies have during tuberculosis?

C Hermann, CG King - Oxford Open Immunology, 2021 - academic.oup.com
Tuberculosis, an infectious disease caused by Mycobacterium tuberculosis (Mtb), is a major
cause of global morbidity and mortality. The primary barrier to the development of an …

Chemical Proteomics Strategies for Analyzing Protein Lipidation Reveal the Bacterial O-Mycoloylome

N Banahene, TM Peters-Clarke, KJ Biegas… - Journal of the …, 2024 - ACS Publications
Protein lipidation dynamically controls protein localization and function within cellular
membranes. A unique form of protein O-fatty acylation in Corynebacterium, termed protein O …

Exploration of novel trehalases from cold-adapted Variovorax sp. PAMC28711: Functional characterization

P Shrestha, J Karmacharya, KH Kim, SR Han… - International Journal of …, 2024 - Elsevier
The cold-adapted bacterium Variovorax sp. PAMC28711 possesses two distinct glycoside
hydrolase (GH) families of trehalase, GH15 and GH37. While numerous studies have …

Impact of MSMEG5257 Deletion on Mycolicibacterium smegmatis Growth

P He, B Zhao, W He, Z Song, S Pei, D Liu, H Xia… - Microorganisms, 2024 - mdpi.com
Mycobacterial membrane proteins play a pivotal role in the bacterial invasion of host cells;
however, the precise mechanisms underlying certain membrane proteins remain elusive …

Non-Microbiological Mycobacterial Detection Techniques for Quality Control of Biological Products: A Comprehensive Review

M Marius, C Fernandez - Microorganisms, 2024 - mdpi.com
Mycobacteria can be one of the main contaminants of biological products, and their
presence can have serious consequences on patients' health. For this reason, the European …

Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface

BA Lepe, CR Zheng, OK Leddy, BL Allsup… - Microbiology …, 2024 - journals.asm.org
Tuberculosis (TB) is the leading cause of infectious disease death and lacks a vaccine
capable of protecting adults from pulmonary TB. The bacterial surface is a critical interface …

Barriers to tuberculosis drug discovery: the mycobacterial cell wall

C Whittaker - 2023 - open.uct.ac.za
The mycobacterial cell wall is a highly complex macromolecular structure that provides
intrinsic resistance to several anti-tuberculosis drugs, making it critical in the success of …

chemical proteomics strategies reveal the bacterial o-mycolome

NM Banahene, TM Peters-Clare… - ADVANCING …, 2023 - search.proquest.com
Protein O-mycoloylation is a post-translational modification in Corynebacterium species and
related bacteria that involves the attachment of mycolic acids—a class of unusual long-chain …