The PAR proteins: from molecular circuits to dynamic self-stabilizing cell polarity

CF Lang, E Munro - Development, 2017 - journals.biologists.com
PAR proteins constitute a highly conserved network of scaffolding proteins, adaptors and
enzymes that form and stabilize cortical asymmetries in response to diverse inputs. They …

[HTML][HTML] The evolution of early neurogenesis

V Hartenstein, A Stollewerk - Developmental Cell, 2015 - cell.com
The foundation of the diverse metazoan nervous systems is laid by embryonic patterning
mechanisms, involving the generation and movement of neural progenitors and their …

Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila

VO Sysoev, B Fischer, CK Frese, I Gupta… - Nature …, 2016 - nature.com
The maternal-to-zygotic transition (MZT) is a process that occurs in animal embryos at the
earliest developmental stages, during which maternally deposited mRNAs and other …

Neurotransmitter identity is acquired in a lineage-restricted manner in the Drosophila CNS

H Lacin, HM Chen, X Long, RH Singer, T Lee… - Elife, 2019 - elifesciences.org
The vast majority of the adult fly ventral nerve cord is composed of 34 hemilineages, which
are clusters of lineally related neurons. Neurons in these hemilineages use one of the three …

Orchestrating morphogenesis: building the body plan by cell shape changes and movements

KZ Perez-Vale, M Peifer - Development, 2020 - journals.biologists.com
During embryonic development, a simple ball of cells re-shapes itself into the elaborate
body plan of an animal. This requires dramatic cell shape changes and cell movements …

Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome

KA Panfilio, IM Vargas Jentzsch, JB Benoit… - Genome biology, 2019 - Springer
Abstract Background The Hemiptera (aphids, cicadas, and true bugs) are a key insect order,
with high diversity for feeding ecology and excellent experimental tractability for molecular …

Drosophila melanogaster as a genetic model system to study neurotransmitter transporters

CA Martin, DE Krantz - Neurochemistry international, 2014 - Elsevier
The model genetic organism Drosophila melanogaster, commonly known as the fruit fly,
uses many of the same neurotransmitters as mammals and very similar mechanisms of …

The cellular and molecular basis of cnidarian neurogenesis

F Rentzsch, M Layden, M Manuel - Wiley Interdisciplinary …, 2017 - Wiley Online Library
Neurogenesis initiates during early development and it continues through later
developmental stages and in adult animals to enable expansion, remodeling, and …

Regulation of Nematostella neural progenitors by SoxB, Notch and bHLH genes

GS Richards, F Rentzsch - Development, 2015 - journals.biologists.com
Notch signalling, SoxB and Group A bHLH 'proneural'genes are conserved regulators of the
neurogenic program in many bilaterians. However, the ancestry of their functions and …

Myosin II promotes the anisotropic loss of the apical domain during Drosophila neuroblast ingression

S Simões, Y Oh, MFZ Wang… - Journal of Cell …, 2017 - rupress.org
Epithelial–mesenchymal transitions play key roles in development and cancer and entail the
loss of epithelial polarity and cell adhesion. In this study, we use quantitative live imaging of …