Convergence of biological and psychological perspectives on cognitive coordination in schizophrenia

WA Phillips, SM Silverstein - Behavioral and Brain Sciences, 2003 - cambridge.org
The concept of locally specialized functions dominates research on higher brain function
and its disorders. Locally specialized functions must be complemented by processes that …

Theory, methods and new directions in the psychophysiology of the schizophrenic process and schizotypy

JH Gruzelier - International Journal of Psychophysiology, 2003 - Elsevier
Theoretical and methodological issues in the psychophysiology of the schizophrenic
process are reviewed. These include the importance of schizotypy with its compensatory …

Schizophrenia: Putting context in context

S Park, J Lee, B Folley, J Kim - Behavioral and Brain Sciences, 2003 - cambridge.org
Although context-processing deficits may be core features of schizophrenia, context remains
a poorly defined concept. To test Phillips & Silverstein's model, we need to operationalize …

No blind schizophrenics: are NMDA-receptor dynamics involved?

GS Sanders, SM Platek, GG Gallup Jr - Behavioral and Brain …, 2003 - cambridge.org
Numerous searches have failed to identify a single co-occurrence of total blindness and
schizophrenia. Evidence that blindness causes loss of certain NMDA-receptor functions is …

Theory of mind in schizophrenia: Damaged module or deficit in cognitive coordination?

D Leiser, U Bonshtein - Behavioral and Brain Sciences, 2003 - cambridge.org
Schizophrenics exhibit a deficit in theory of mind (ToM), but an intact theory of biology (ToB).
One explanation is that ToM relies on an independent module that is selectively damaged …

Cognitive coordination and its neurobiological bases: A new continent to explore

SM Silverstein, WA Phillips - Behavioral and Brain Sciences, 2003 - cambridge.org
The additional arguments and evidence supplied by the commentaries strengthen the
hypothesis that underactivity of NMDA receptors produces impaired cognitive coordination …

NMDA synapses can bias competition between object representations and mediate attentional selection

A Raffone, JMJ Murre, G Wolters - Behavioral and Brain Sciences, 2003 - cambridge.org
Phillips & Silverstein emphasize the gain-control properties of NMDA synapses in cognitive
coordination. We endorse their view and suggest that NMDA synapses play a crucial role in …

Mechanisms of disrupted language comprehension in schizophrenia

R Condray, SR Steinhauer - Behavioral and Brain Sciences, 2003 - cambridge.org
Mechanisms that contribute to perceptual processing dysfunction in schizophrenia were
examined by Phillips & Silverstein, and formulated as involving disruptions in both local and …

Peeling the onion: NMDA dysfunction as a unifying model in schizophrenia

DC Javitt - Behavioral and Brain Sciences, 2003 - cambridge.org
N-methyl-d-aspartate receptor (NMDAR) dysfunction plays a crucial role in schizophrenia,
leading to impairments in cognitive coordination. NMDAR agonists (eg, glycine) ameliorate …

Context rules

SL Bressler - Behavioral and Brain Sciences, 2003 - cambridge.org
It is proposed that cortical activity is normally coordinated across synaptically connected
areas and that this coordination supports cognitive coherence relations. This view is …