The chaperone balance hypothesis: The importance of the extracellular to intracellular HSP70 ratio to inflammation‐driven type 2 diabetes, the effect of exercise, and …

M Krause, TG Heck, A Bittencourt… - Mediators of …, 2015 - Wiley Online Library
Recent evidence shows divergence between the concentrations of extracellular 70 kDa heat
shock protein [eHSP70] and its intracellular concentrations [iHSP70] in people with type 2 …

Extracellular heat shock proteins: a new location, a new function

A De Maio, D Vazquez - Shock, 2013 - journals.lww.com
The expression of heat shock proteins (HSPs) is a basic and well-conserved cellular
response to an array of stresses. These proteins are involved in the repair of cellular …

Consensus statement immunonutrition and exercise.

S Bermon, LM Castell, PC Calder… - Exercise …, 2017 - researchonline.ljmu.ac.uk
In this consensus statement on immunonutrition and exercise, a panel of knowledgeable
contributors from across the globe provides a consensus of updated science, including the …

Inflammatory/stress feedback dysregulation in women with fibromyalgia

ME Bote, JJ García, MD Hinchado, E Ortega - Neuroimmunomodulation, 2012 - karger.com
Objective: Although one of the current hypotheses of the aetiology of fibromyalgia (FM)
syndrome involves inflammatory and neuroendocrine disorders, its biophysiology still …

Fibromyalgia: anti-inflammatory and stress responses after acute moderate exercise

ME Bote, JJ Garcia, MD Hinchado, E Ortega - PloS one, 2013 - journals.plos.org
Fibromyalgia (FM) is characterized in part by an elevated inflammatory status, and “modified
exercise” is currently proposed as being a good therapeutic help for these patients …

Extracellular Hsp70: export and function

A De Maio - Current Protein and Peptide Science, 2014 - ingentaconnect.com
The most conserved cellular response to stress is the expression of heat shock proteins
(hsp). These proteins participate in the repair of cellular damage after the stress, which is …

[HTML][HTML] Divergence of intracellular and extracellular HSP72 in type 2 diabetes: does fat matter?

J Rodrigues-Krause, M Krause, C O'Hagan… - Cell Stress and …, 2012 - Elsevier
Mammalian cells have developed a range of adaptations to survive against acute and
prolonged (but not lethal) stresses (Beckmann et al. 1992). Among these adaptations, the …

Effects of 30 min of aerobic exercise on gene expression in human neutrophils

S Radom-Aizik, F Zaldivar Jr, SY Leu… - Journal of applied …, 2008 - journals.physiology.org
Relatively brief bouts of exercise alter gene expression in peripheral blood mononuclear
cells (PBMCs), but whether exercise changes gene expression in circulating neutrophils …

Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistance in vivo and cause pancreatic β-cell dysfunction and …

M Krause, K Keane, J Rodrigues-Krause… - Clinical …, 2014 - portlandpress.com
eHSP72 (extracellular heat-shock protein 72) is increased in the plasma of both types of
diabetes and is positively correlated with inflammatory markers. Since aging is associated …

[HTML][HTML] Heat shock response during the resolution of inflammation and its progressive suppression in chronic-degenerative inflammatory diseases

HT Schroeder, CHDL Muller, TG Heck, M Krause… - Cell Stress and …, 2024 - Elsevier
The heat shock response (HSR) is a crucial biochemical pathway that orchestrates the
resolution of inflammation, primarily under proteotoxic stress conditions. This process hinges …