The first aim of the present review is to provide an in-depth description of the cannabinoids
and their known effects at various neuronal receptors. It reveals that cannabinoids are highly …

Fear extinction leads to a decrease of originally acquired fear responses after the threat is
no longer present. Fear extinction is adaptive and critical for organism's survival, but deficits …

Background: Δ9-Tetrahydrocannabinol (THC, a CB1 receptor agonist) and Cannabidiol
(CBD, a non-competitive antagonist of endogenous CB1 and CB2 ligands) are two primary …

The amygdala, a critical brain region responsible for emotional behavior, is crucially
involved in the regulation of the effects of stress on emotional behavior. In the mammalian …

Memory extinction is referred to as a learning process in which a conditioned response (CR)
progressively reduces over time as an animal learns to uncouple a response from a …

Background: Souroubea sympetala Gilg. is a neotropical vine native to Central America,
investigated as part of a targeted study of the plant family Marcgraviaceae. Our previous …

Fear extinction is an adaptive behavioral process critical for organism's survival, but
deficiency in extinction may lead to PTSD. While the amygdala and its neural circuits are …

Post-traumatic stress disorder is a disorder characterized by an inability to extinguish
traumatic memories and heightened reactivity to emotional stimuli. Due to the heightened …

The aim of this study was to investigate the influence of a polymorphism in the serotonin
transporter gene (5-HTTLPR) in patients diagnosed with posttraumatic stress disorder …