Detection of high‐risk human papillomavirus E6 and E7 oncogene transcripts in cervical scrapes by nested RT‐polymerase chain reaction

K Sotlar, A Stubner, D Diemer, S Menton… - Journal of medical …, 2004 - Wiley Online Library
The oncogenic potential of the high‐risk human papillomavirus (HPV) genotypes (types 16,
18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68) depends on the expression of the two …

[HTML][HTML] Usefulness, methods and rationale of lymph nodes HPV-DNA investigation in estimating risk of early stage cervical cancer recurrence: a systematic literature …

M Noventa, E Ancona, E Cosmi, C Saccardi… - Clinical & experimental …, 2014 - Springer
Metastatic involvement of pelvic lymph-nodes (LNs), generally found in 0–29.3% of early
stages, is the most important prognostic factor in cervical cancer (CC). However, even in non …

Expression of dominant negative Jun inhibits elevated AP-1 and NF-κB transactivation and suppresses anchorage independent growth of HPV immortalized human …

JJ Li, JS Rhim, R Schlegel, KH Vousden, NH Colburn - Oncogene, 1998 - nature.com
AP-1 transactivation appears to be required for mouse JB6 cell neoplastic transformation
induced by the tumor promoter TPA or epidermal growth factor (EGF). Exposure to AP-1 …

Ubiquitous presence of E6 and E7 transcripts in human papillomavirus—Positive cervical carcinomas regardless of its type

S Nakagawa, H Yoshikawa, T Yasugi… - Journal of medical …, 2000 - Wiley Online Library
The presence of human papillomavirus (HPV) DNA in almost all of the cervical carcinomas
is one of the most compelling evidence for the viral carcinogenesis. HPVs are thought to …

Induced expression of dominant‐negative c‐jun downregulates NFκB and AP‐1 target genes and suppresses tumor phenotype in human keratinocytes

JJ Li, Y Cao, MR Young… - … : Published in cooperation …, 2000 - Wiley Online Library
Neoplastically transformed mouse and human keratinocytes elevate transactivation of both
activator protein 1 (AP‐1) and nuclear factor κB (NFκB) transcription factors. The present …

Can a test for E6/E7 transcripts of human papillomavirus type 16 serve as a diagnostic tool for the detection of micrometastasis in cervical cancer?

J Czeglédy, C Iosif, BG Hansson… - … journal of cancer, 1995 - Wiley Online Library
Tissue from 11 cases of cervical cancer positive for human papillomavirus (HPV) type 16
DNA and 69 pelvic lymph nodes from the same patients were examined for HPV 16 DNA …

Incidence of human papillomavirus 16 and 18 infection and p53 mutation in patients with oral squamous cell carcinoma in Japan

K Shima, I Kobayashi, I Saito, T Kiyoshima… - British Journal Of Oral …, 2000 - Elsevier
The purpose of this study was to investigate the prevalence of human papillomaviruses
(HPVs) 16 and 18 infection, and p53 mutation in oral squamous cell carcinomas (SCCs) in …

Differential splicing of E6 within human papillomavirus type 18 variants and functional consequences

E De la Cruz-Hernández… - Journal of general …, 2005 - microbiologyresearch.org
Persistent infections of the uterine cervix with 'high-risk'human papillomavirus (HPV) are
now recognized as necessary for the development of cervical cancer. Among them, HPV …

Correlation of human papillomavirus 16 and 18 with prognostic factors in invasive cervical neoplasias

J Kónya, G Veress, Z Hernádi, G Soós… - Journal of medical …, 1995 - Wiley Online Library
Forty‐seven patients with cervical carcinoma were examined in order to correlate human
papillomavirus (HPV) types with prognostic factors in invasive cervical neoplasias. Age …

Detection of human papilloma virus DNA in lymph nodes extirpated at radical surgery for cervical cancer is not predictive of recurrence

J Czeglédy, C Iosif, O Forslund, R Willén… - Journal of medical …, 1998 - Wiley Online Library
In women with recurrent cervical cancer after radical surgery, lymph node metastasis is
detectable histologically at the time of surgery in only about 50% of cases. The present study …