The tumor microenvironment in the postsurgical liver: Mechanisms and potential targets of postoperative recurrence in human hepatocellular carcinoma

J Wu, YT Chan, Y Lu, N Wang… - Medicinal Research …, 2023 - Wiley Online Library
Surgery remains to be the mainstay of treatment for hepatocellular carcinoma (HCC).
Nonetheless, its therapeutic efficacy is significantly impaired by postoperative recurrence …

The crosstalking immune cells network creates a collective function beyond the function of each cellular constituent during the progression of hepatocellular …

N Koelsch, F Mirshahi, HF Aqbi, M Saneshaw… - Scientific Reports, 2023 - nature.com
Abundance of data on the role of inflammatory immune responses in the progression or
inhibition of hepatocellular carcinoma (HCC) has failed to offer a curative immunotherapy for …

Research progress of protein induced by vitamin K absence or antagonist II in liver transplantation for hepatocellular carcinoma

Z Zhou, Q Liu, J Liu, W Li, S Cao, J Xu, J Chen, X Xu… - Heliyon, 2024 - cell.com
Hepatocellular carcinoma (HCC) is the most common pathologic type of primary liver
cancer. Liver transplantation (LT) is a radical strategy for treating patients with early-stage …

More balance toward activating receptors and cytotoxic activity of NK cells ex vivo differentiated from human umbilical cord blood-derived CD34+ stem cells in …

F Ghaedrahmati, N Esmaeil, V Akbari, F Ashrafi - Heliyon, 2024 - cell.com
Adoptive immunotherapies that use functional NK cells depend on the availability of
sufficient numbers of these cells. We expanded umbilical cord blood (UCB)-CD34+ HSCs for …

[PDF][PDF] Nicholas Koelsch 1Ε, Faridoddin Mirshahi 2, Hussein F. Aqbi 3, Mulugeta Saneshaw 2

MO Idowu, AL Olex, AJ Sanyal, MH Manjili - Scientific Reports, 2023 - researchgate.net
Results Progression of NAFLD and HCC are associated with remodeling of the hepatic
structural cells, fibroblasts and endothelial cells, associated with shifts from predominant T …

Donor Age Correlates With Liver-Resident Natural Killer Cell Activity in Adoptive Immunotherapy Using Donor Liver Natural Killer Cells in Liver Transplantation

M Ohira, K Imaoka, T Bekki, K Sato, Y Imaoka… - Transplantation …, 2024 - Elsevier
Background Natural killer (NK) cells are involved in innate immunity and have been reported
to play an important role in hepatocellular carcinoma recurrence and post-liver …

The hepatic immunological pattern shaped by dominant-subdominant cellular interactions creates a collective function beyond the function of each cellular constituent …

NJ Koelsch - 2023 - scholarscompass.vcu.edu
Abundance of data on the role of inflammatory immune responses in the progression or
inhibition of hepatocellular carcinoma (HCC) has failed to offer a curative immunotherapy for …

肝内在natural killer 細胞を用いた免疫細胞療法

大段秀樹, 大平真裕 - 外科と代謝・栄養, 2023 - jstage.jst.go.jp
抄録 肝臓には, 特定の成熟期にある natural killer (NK) 細胞が局在し, 強力な抗腫瘍分子 TNF‐
related apoptosis inducing ligand (TRAIL) が誘導可能で, TRAIL 受容体を高発現する中・低分化 …