Genetic elements coding for proteins that present amino acid identity with the conserved
motifs of retroviral reverse transcriptases constitute the retroid family. With the exception of …

Both retroviruses and long terminal repeat (LTR) retrotransposons use cellular tRNAs as
primers for reverse transcription during their replication cycles. In retroviruses, primer tRNA …

Telomeres are nanoscale DNA–protein complexes to protect and stabilize chromosomes.
The reexpression of telomerase in cancer cells is a key determinant crucial for the infinite …

Telomerase, a multi-subunit ribonucleoprotein complex, is a unique reverse transcriptase
that catalyzes the processive addition of a repeat sequence to extend the telomere end …

The ability of human immunodeficiency virus‐1 (HIV‐1) to undergo efficient reverse
transcription is dependent on a number of parameters. These include the binding of the …

Replication of the human immunodeficiency virus type 1 (HIV-1) and other retroviruses
involves reverse transcription of the viral RNA genome into a double-stranded DNA. This …

SUMMARY SARS-CoV-2, the etiological agent responsible for the COVID-19 pandemic, is a
member of the virus family Coronaviridae, known for relatively extensive (~ 30-kb) RNA …

The initiation of human immunodeficiency virus type 1 (HIV-1) reverse transcription occurs at
a site in the viral RNA genome which is designated the primer-binding site (PBS). The HIV-1 …

The human immunodeficiency virus type 1 genomic RNA primer-binding site (PBS)
sequence comprises 18 nucleotides which are complementary to those at the 3'end of the …

The initiation of human immunodeficiency virus type 1 reverse transcription occurs by
extension of a tRNA (Lys3) primer bound near the 5'end of the viral RNA genome which is …