While ultrasound is most widely known for its use in diagnostic imaging, the energy carried
by ultrasound waves can be utilized to influence cell function and drug delivery …

Novel drug delivery systems based on microtechnology have advanced tremendously, but
yet face some technological and societal hurdles to fully achieve their potential. The novel …

Protecting and promoting public health is the mission of the US Food and Drug
Administration (FDA). FDA's Center for Devices and Radiological Health (CDRH), which …

Corneal disease remains a leading cause of impaired vision world-wide, and advancements
in gene therapy continue to develop with promising success to prevent, treat and cure …

Inflammation is the underlying process of several diseases within the eye, specifically in the
cornea. Current treatment options for corneal inflammation or keratitis, and related …

Studying the formation and stability of atherosclerotic plaques in the hemodynamic field is
essential for understanding the growth mechanism and preventive treatment of …

Experimental studies have shown that ultrasonic cavitation can reversibly open the blood–
brain barrier (BBB) to assist drug delivery. Nevertheless, the majority of the present study …

Purpose: The objective of this study was to utilize therapeutic ultrasound in enhancing
delivery of topical macromolecules into the cornea. Methods: Rabbit corneas were dissected …

Purpose: The purpose of this study was to characterize whether pulsed ultrasound (PUS)
affects transscleral drug delivery. Methods: Fluorescein sodium (NaF, 376 Da) and …

Purpose: Macromolecules have been shown to be effective in vision-saving treatments for
various ocular diseases, such as age-related macular degeneration and diabetic …