Neuroprotective natural products for Alzheimer's disease

X Chen, J Drew, W Berney, W Lei - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is the number one neurovegetative disease, but its treatment
options are relatively few and ineffective. In efforts to discover new strategies for AD therapy …

Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies

D Tromp, A Dufour, S Lithfous, T Pebayle… - Ageing research …, 2015 - Elsevier
Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

l-Carnitine and Acetyl-l-carnitine Roles and Neuroprotection in Developing Brain

GC Ferreira, MC McKenna - Neurochemical research, 2017 - Springer
Abstract l-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for
degradation by β-oxidation. Treatment with l-carnitine can ameliorate metabolic imbalances …

The amygdala modulates the consolidation of memories of emotionally arousing experiences

JL McGaugh - Annu. Rev. Neurosci., 2004 - annualreviews.org
▪ Abstract Converging findings of animal and human studies provide compelling evidence
that the amygdala is critically involved in enabling us to acquire and retain lasting memories …

Organophosphate pesticide exposure and neurodegeneration

F Sánchez-Santed, MT Colomina, EH Hernández - Cortex, 2016 - Elsevier
Organophosphate pesticides (OPs) are used extensively throughout the world. The main
sources of contamination for humans are dietary ingestion and occupational exposures. The …

The value of spontaneous alternation behavior (SAB) as a test of retention in pharmacological investigations of memory

RN Hughes - Neuroscience & Biobehavioral Reviews, 2004 - Elsevier
Because of its reliance on memory, the tendency for rats, mice and other animals to alternate
successive choices of T-or Y-maze arms has assumed considerable popularity in …

Neurobiology of decision making: a selective review from a neurocognitive and clinical perspective

M Ernst, MP Paulus - Biological psychiatry, 2005 - Elsevier
We present a temporal map of key processes that occur during decision making, which
consists of three stages: 1) formation of preferences among options, 2) selection and …

Multiple memory subsystems: reconsidering memory in the mind and brain

BE Sherman, NB Turk-Browne… - Perspectives on …, 2024 - journals.sagepub.com
The multiple-memory-systems framework—that distinct types of memory are supported by
distinct brain systems—has guided learning and memory research for decades. However …

Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application

MJ Millan - Pharmacology & therapeutics, 2006 - Elsevier
Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

Emotion, motivation, and the brain: reflex foundations in animal and human research

PJ Lang, M Davis - Progress in brain research, 2006 - Elsevier
This review will focus on a motivational circuit in the brain, centered on the amygdala, that
underlies human emotion. This neural circuitry of appetitive/approach and …