The magic of proteases: from a procoagulant and anticoagulant factor V to an equitable treatment of its inherited deficiency

JA De Pablo-Moreno, A Miguel-Batuecas… - International Journal of …, 2023 - mdpi.com
Proteostasis, ie, the homeostasis of proteins, responsible for ensuring protein turnover, is
regulated by proteases, which also participate in the etiopathogenesis of multiple conditions …

PfEMP1 and var genes-Still of key importance in Plasmodium falciparum malaria pathogenesis and immunity

L Hviid, AR Jensen, KW Deitsch - Advances in …, 2024 - pubmed.ncbi.nlm.nih.gov
The most severe form of malaria, caused by infection with Plasmodium falciparum parasites,
continues to be an important cause of human suffering and poverty. The P. falciparum …

Profiles of global mutations in the human intercellular adhesion molecule-1 (ICAM-1) shed light on population-specific malaria susceptibility

J Gill, H Singh, A Sharma - BMC genomics, 2023 - Springer
Plasmodium falciparum is responsible for malaria-related morbidity and mortality. PfEMP1
(P. falciparum erythrocyte membrane protein 1) mediates infected erythrocytes adhesion to …