Ultra high-plex spatial proteogenomic investigation of giant cell glioblastoma multiforme immune infiltrates reveals distinct protein and RNA expression profiles
SA Bonnett, AB Rosenbloom, GT Ong, M Conner… - Cancer Research …, 2023 - AACR
A deeper understanding of complex biological processes, including tumor development and
immune response, requires ultra high-plex, spatial interrogation of multiple “omes”. Here we …
immune response, requires ultra high-plex, spatial interrogation of multiple “omes”. Here we …
Computer-assisted tumor grading, validation of PD-L1 scoring, and quantification of CD8-positive immune cell density in urothelial carcinoma, a visual guide for …
A Rodrigues, C Nogueira, LC Marinho… - Surgical and …, 2022 - Springer
Background Advances in digital imaging in pathology and the new capacity to scan high-
quality images have change the way to practice and research in surgical pathology. QuPath …
quality images have change the way to practice and research in surgical pathology. QuPath …
PixlMap: A generalisable pixel classifier for cellular phenotyping in multiplex immunofluorescence images
RL Pennie, D Mason, K Rakovic, F Ballantyne… - bioRxiv, 2025 - biorxiv.org
Multiplexed methods for the detection of protein expression generate extremely data-rich
images of intact tissue sections. These images are invaluable for the quantification and …
images of intact tissue sections. These images are invaluable for the quantification and …