Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural Product …, 2015 - pubs.rsc.org
Covering: 2013. Previous review: Nat. Prod. Rep., 2014, 31, 160–258 This review covers the
literature published in 2013 for marine natural products (MNPs), with 982 citations (644 for …

Bioactive metabolites from marine algae as potent pharmacophores against oxidative stress-associated human diseases: A comprehensive review

B Pradhan, R Nayak, S Patra, BP Jit, A Ragusa, M Jena - Molecules, 2020 - mdpi.com
In addition to cancer and diabetes, inflammatory and ROS-related diseases represent one of
the major health problems worldwide. Currently, several synthetic drugs are used to reduce …

Recent updates on development of protein-tyrosine phosphatase 1B inhibitors for treatment of diabetes, obesity and related disorders

S Singh, AS Grewal, R Grover, N Sharma, B Chopra… - Bioorganic …, 2022 - Elsevier
The aim of this review was to discuss an overview of type 2 diabetes; biology of PTP1B; role
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …

Marine organisms with anti-diabetes properties

C Lauritano, A Ianora - Marine drugs, 2016 - mdpi.com
Diabetes is a chronic degenerative metabolic disease with high morbidity and mortality rates
caused by its complications. In recent years, there has been a growing interest in looking for …

Natural and semisynthetic protein tyrosine phosphatase 1B (PTP1B) inhibitors as anti-diabetic agents

LJ Wang, B Jiang, N Wu, SY Wang, DY Shi - RSC Advances, 2015 - pubs.rsc.org
Diabetes mellitus, which includes both type 1 and type 2 diabetes mellitus (T2DM), is a
major disease that threatens human health worldwide. Protein tyrosine phosphatase 1B …

Recent advances in the development of protein tyrosine phosphatase 1B inhibitors for Type 2 diabetes

S Qian, M Zhang, Y He, W Wang… - Future Medicinal Chemistry, 2016 - Taylor & Francis
Diabetes mellitus is the most serious and prevalent metabolic disorders worldwide,
complications of which can decrease significantly the quality of life and contribute to …

Verruculides A and B, two new protein tyrosine phosphatase 1B inhibitors from an Indonesian ascidian-derived Penicillium verruculosum

H Yamazaki, W Nakayama, O Takahashi… - Bioorganic & Medicinal …, 2015 - Elsevier
Two new merosesquiterpenes, verruculides A (1) and B (2), were isolated from a culture
broth of the Indonesian ascidian-derived Penicillium verruculosum TPU1311, together with …

Marine resources effective in controlling and treating diabetes and its associated complications

SB Nasab, A Homaei, BI Pletschke… - Process …, 2020 - Elsevier
Diabetes is a metabolic disorder characterized by a chronic increase in blood glucose. This
disease is a major threat to public health and is one of the main causes of mortality in …

Natural Bioactive Compounds from Marine Invertebrates That Modulate Key Targets Implicated in the Onset of Type 2 Diabetes Mellitus (T2DM) and Its Complications

M Casertano, A Vito, A Aiello, C Imperatore, M Menna - Pharmaceutics, 2023 - mdpi.com
Background: Type 2 diabetes mellitus (T2DM) is an ongoing, risky, and costly health
problem that therefore always requires new treatment options. Moreover, although several …

Natural products from sponges

BN Han, LL Hong, BB Gu, YT Sun, J Wang… - … Microbiomes of Coral …, 2019 - Springer
The sponge is one of the oldest multicellular invertebrates in the world. Marine sponges
represent one of the extant metazoans of 700–800 million years. They are classified in four …