Persistent neutrophilic inflammation is a central feature in both the pathogenesis and
progression of bronchiectasis. Neutrophils release neutrophil serine proteases (NSPs), such …

Chemokines and their receptors play important roles in the pathophysiology of many
diseases by regulating the cellular migration of major inflammatory and immune players …

Initially thought to be homogenous and short-lived with limited function, neutrophils are now
recognised as critical and dynamic immune cells with longer life spans than previously …

During recovery from septic shock, circulating mitochondrial N-formyl peptides predispose to
secondary infection by occupying formyl peptide receptor 1 on the neutrophil …

Neutrophils are an important cell type often considered the body's" first responder" in the
response to inflammatory insult or damage. They are recruited to the tissue of the lungs …

Introduction Brain death (BD) is known to compromise graft quality by causing
hemodynamic, metabolic, and hormonal changes. The abrupt reduction of female sex …

Background Environmental/occupational exposures cause significant lung diseases.
Agricultural organic dust extracts (ODE) and bacterial component lipopolysaccharide (LPS) …

Abstract Coronavirus disease 2019 (COVID-19) continues as a global pandemic. Patients
with lung cancer infected with COVID-19 may develop severe disease or die. Treating such …

While hypogammaglobulinemia is associated with COPD exacerbations, it is unknown
whether frequent exacerbators have specific defects in antibody production/function. We …

G-protein-coupled receptors (GPCRs) are the molecular target of 40% of marketed drugs
and the most investigated structures to develop novel therapeutics. Different members of the …