The mitochondrial permeability transition (PT) is a permeability increase of the inner
mitochondrial membrane mediated by a channel, the permeability transition pore (PTP) …

Since the chemiosmotic theory was proposed by Peter Mitchell in the 1960s, a major
objective has been to elucidate the mechanism of coupling of the transmembrane proton …

We determined the structure of a complete, dimeric F 1 F o-ATP synthase from yeast
Yarrowia lipolytica mitochondria by a combination of cryo-EM and X-ray crystallography. The …

The inner membrane of the mitochondrion folds inwards, forming the cristae. This folding
allows a greater amount of membrane to be packed into the mitochondrion. The data in this …

Specific modules and subcomplexes like F1 and FOF0-parts, F1-c subcomplexes, peripheral
and central stalks, and the rotor part comprising a ring of c-subunits with attached subunits γ …

We review recent advances in understanding of the structure of the F 1 F 0‐ATP synthase of
the mitochondrial inner membrane (mtATPase). A significant achievement has been the …

Oligomycin has long been known as an inhibitor of mitochondrial ATP synthase, putatively
binding the F o subunits 9 and 6 that contribute to proton channel function of the complex. As …

Blue native polyacrylamide gel electrophoresis (BN-PAGE) analyses of detergent
mitochondrial extracts have provided evidence that the yeast ATP synthase could form …

Mitochondrial F1Fo ATP synthase is an enzymatic complex involved in the aerobic synthesis
of ATP. It is well known that several enzymes are organized in supramolecular complexes in …

A method for sodium dodecyl sulfate (SDS) quantitation in microliter-volume complex
biochemical samples is described. The quantitation is based on the use of a dye, stains-all …