High-Grade Subarachnoid Hemorrhage-Beyond Guidelines

S Wyckoff, SHY Chou - Neurologic Clinics, 2025 - neurologic.theclinics.com
Spontaneous subarachnoid hemorrhage (SAH), commonly caused by the rupture of an
intracerebral aneurysm (85% of all cases of SAH), remains a life-threatening condition with …

Contemporary management of aneurysmal subarachnoid haemorrhage. An update for the intensivist

C Robba, KM Busl, J Claassen, MN Diringer… - Intensive Care …, 2024 - Springer
Aneurysmal subarachnoid haemorrhage (aSAH) is a rare yet profoundly debilitating
condition associated with high global case fatality and morbidity rates. The key determinants …

Hemodynamic response and clinical outcome following intravenous milrinone plus norepinephrine–based hyperdynamic hypertensive therapy in patients suffering …

HJ Steiger, R Ensner, L Andereggen, L Remonda… - Acta …, 2022 - Springer
Purpose Intravenous and intra-arterial milrinone as a rescue measure for delayed cerebral
ischemia (DCI) after subarachnoid hemorrhage (SAH) has been adopted by several groups …

Pharmaceutical novel solid forms of Milrinone with advanced physicochemical properties

L Giri, SR Rout, A Kar, G Kenguva… - Journal of Molecular …, 2022 - Elsevier
Milrinone (MLN) is a second-generation bipyridine phosphodiesterase (PDE) inhibitor
developed by modifying amrinone chemically. It is a PDE-III antagonist that promotes …

CT perfusion-guided administration of IV milrinone is associated with a reduction in delayed cerebral infarction after subarachnoid hemorrhage

V Szabo, S Baccialone, F Kucharczak, C Dargazanli… - Scientific Reports, 2024 - nature.com
Delayed cerebral ischemia (DCI) after aneurysmal subarachnoid haemorrhage (aSAH) is a
singular pathological entity necessitating early diagnostic approaches and both prophylactic …

Effect of inotropic agents on oxygenation and cerebral perfusion in acute brain injury

G Coppalini, E Duvigneaud, A Diosdado… - Frontiers in …, 2022 - frontiersin.org
Introduction Tissue hypoxia and insufficient energy delivery is one of the mechanisms
behind the occurrence of several complications in acute brain injured patients. Several …

Treating Vasospasm with IV Milrinone: Relax (The Vessel) or Don't Do It!

V Robert-Edan, K Lakhal - Neurocritical Care, 2023 - Springer
We read with great interest the practice guidance article by Deem et al.[1] regarding the
hemodynamic management in the prevention and treatment of delayed cerebral ischemia …

Nimodipine vs. Milrinone–Equal or Complementary Use? A Retrospective Analysis

J Jentzsch, S Ziganshyna, D Lindner, H Merkel… - Frontiers in …, 2022 - frontiersin.org
Background Cerebral vasospasm (CVS) continues to account for high morbidity and
mortality in patients surviving the initial aneurysmal subarachnoid hemorrhage (SAH) …

Milrinone for the treatment of heart failure caused by severe Pneumonia in children with congenital heart disease: a meta-analysis

W Shao, S Diao, L Zhou, L Cai - BMC pediatrics, 2023 - Springer
Background Children with congenital heart disease (CHD) are easily complicated by severe
pneumonia and heart failure. We aimed to conduct a meta-analysis to evaluate the effects …

Spectral Properties Echoing the Tautomerism of Milrinone and Its Application to Fe3+ Ion Sensing and Protein Staining

H Zhu, P Ma, Y Qian, J Xia, F Gong, L Chen, L Xu - Biosensors, 2022 - mdpi.com
Knowledge on the spectral properties of the tautomers of milrinone (MLR) in solvents and
solid-state, as well as under light conditions is of critical importance from both theoretical …