Computational approaches to therapeutic antibody design: established methods and emerging trends
Antibodies are proteins that recognize the molecular surfaces of potentially noxious
molecules to mount an adaptive immune response or, in the case of autoimmune diseases …
molecules to mount an adaptive immune response or, in the case of autoimmune diseases …
The advances in brucellosis vaccines
H Hou, X Liu, Q Peng - Vaccine, 2019 - Elsevier
Brucellosis is a worldwide zoonosis affecting animal and human health. Till now, there is no
effective vaccine licensed for brucellosis in humans. Although M5, H38 and 45/20 vaccines …
effective vaccine licensed for brucellosis in humans. Although M5, H38 and 45/20 vaccines …
Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches
SARS-CoV-2 causes a severe respiratory disease called COVID-19. Currently, global health
is facing its devastating outbreak. However, there is no vaccine available against this virus …
is facing its devastating outbreak. However, there is no vaccine available against this virus …
Designing multi-epitope vaccines to combat emerging coronavirus disease 2019 (COVID-19) by employing immuno-informatics approach
A recent pandemic caused by a single-stranded RNA virus, COVID-19, initially discovered in
China, is now spreading globally. This poses a serious threat that needs to be addressed …
China, is now spreading globally. This poses a serious threat that needs to be addressed …
Design of a multi-epitope-based vaccine targeting M-protein of SARS-CoV2: an immunoinformatics approach
VS Ayyagari, V TC, AP K, K Srirama - Journal of biomolecular …, 2022 - Taylor & Francis
In the present study, one of the targets present on the envelopes of coronaviruses,
membrane glycoprotein (M) was chosen for the design of a multi-epitope vaccine by …
membrane glycoprotein (M) was chosen for the design of a multi-epitope vaccine by …
Predicting epitopes for vaccine development using bioinformatics tools
V Yurina, OR Adianingsih - Therapeutic advances in …, 2022 - journals.sagepub.com
Epitope-based DNA vaccine development is one application of bioinformatics or in silico
studies, that is, computational methods, including mathematical, chemical, and biological …
studies, that is, computational methods, including mathematical, chemical, and biological …
[HTML][HTML] Immunoinformatics and molecular modeling approach to design universal multi-epitope vaccine for SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmittable
and pathogenic human coronavirus that caused a pandemic situation of acute respiratory …
and pathogenic human coronavirus that caused a pandemic situation of acute respiratory …
Structural basis and designing of peptide vaccine using PE-PGRS family protein of Mycobacterium ulcerans—An integrated vaccinomics approach
Buruli ulcer is an emerging tissue-necrosis infectious disease, caused by the pathogen
Mycobacterium ulcerans, leading to permanent deformity if untreated. Despite this …
Mycobacterium ulcerans, leading to permanent deformity if untreated. Despite this …
Multiepitope-based subunit vaccine design and evaluation against respiratory syncytial virus using reverse vaccinology approach
Respiratory syncytial virus (RSV) is primarily associated with respiratory disorders globally.
Despite the availability of information, there is still no competitive vaccine available for RSV …
Despite the availability of information, there is still no competitive vaccine available for RSV …
Vaccination with a novel multi-epitope ROP8 DNA vaccine against acute Toxoplasma gondii infection induces strong B and T cell responses in mice
Rhoptry proteins (ROPs) are involved in the cell invasion and parasitophorous vacuole (PV)
formation and also vital for survival of Toxoplasma gondii (T. gondii) within host cells. ROP8 …
formation and also vital for survival of Toxoplasma gondii (T. gondii) within host cells. ROP8 …