Glycointeractions in bacterial pathogenesis

J Poole, CJ Day, M von Itzstein, JC Paton… - Nature Reviews …, 2018 - nature.com
Many important interactions between bacterial pathogens and their hosts are highly specific
binding events that involve host or pathogen carbohydrate structures (glycans). Glycan …

Anti-tick vaccines

P Willadsen - Parasitology, 2004 - cambridge.org
There is now abundant evidence that vaccination with defined protein antigens is able to
induce significant immunity to tick infestation. In a limited number of cases, this immunity has …

Synapsin I is an oligomannose-carrying glycoprotein, acts as an oligomannose-binding lectin, and promotes neurite outgrowth and neuronal survival when released …

S Wang, F Cesca, G Loers, M Schweizer… - Journal of …, 2011 - Soc Neuroscience
Oligomannosidic glycans play important roles in nervous system development and function.
By performing a phage display screening with oligomannose-specific antibodies, we …

Epitope identification and discovery using phage display libraries: applications in vaccine development and diagnostics

LF Wang, M Yu - Current drug targets, 2004 - ingentaconnect.com
Antigenic epitopes are the part (contact points) of an antigen involved in specific interaction
with the antigen-binding site (the paratope) of an antibody or a T-cell receptor. Detailed …

Allergen microarray: comparison of microarray using recombinant allergens with conventional diagnostic methods to detect allergen‐specific serum immunoglobulin E

B Jahn‐Schmid, C Harwanegg, R Hiller… - Clinical & …, 2003 - Wiley Online Library
Background The availability of recombinant allergens and recent advances in biochip
technology led to the development of a novel test system for the detection of allergen …

Progress and new technologies for developing vaccines against gastrointestinal nematode parasites of sheep

SE Newton, ENT Meeusen - Parasite immunology, 2003 - Wiley Online Library
Despite the identification of highly effective native antigens for vaccination against
Haemonchus contortus, particularly 'hidden'antigens derived from the intestine of adult …

Enhancement of the immunogenicity of synthetic carbohydrate vaccines by chemical modifications of STn antigen

F Yang, XJ Zheng, CX Huo, Y Wang… - ACS chemical …, 2011 - ACS Publications
The abnormal glycans expressed on the surface of tumor cells, known as tumor-associated
carbohydrate antigens, increase the chance to develop carbohydrate-based anticancer …

Peptide mimotopes to emulate carbohydrates

T Matsubara - Chemical Society Reviews, 2022 - pubs.rsc.org
Glycoconjugates on animal cell surfaces are involved in numerous biological functions and
diseases, especially the adhesion/metastasis of cancer cells, infection, and the onset of …

Inhibition and detection of galectins

RJ Pieters - ChemBioChem, 2006 - Wiley Online Library
More and more studies report on the roles that galectins play in numerous types of cancer.
These roles can be varied, as has been shown particularly for galectin‐3. These studies …

Phage display for epitope determination: A paradigm for identifying receptor-ligand interactions Merrill J. Rowley*, Karen O'Connor, and Lakshmi Wijeyewickrema …

MJ Rowley - Biotechnology annual review, 2004 - books.google.com
Antibodies that react with many different molecular species of protein and non-protein nature
are widely studied in biology and have particular utilities, but the precise epitopes …