Cardiovascular disease is a leading cause of morbidity and mortality in individuals with
Down syndrome. Congenital heart disease is the most common cardiovascular condition in …

Down's syndrome (DS) presents with a constellation of cardiac, neurocognitive and growth
impairments. Individuals with DS are also prone to severe infections and autoimmunity …

The endocrine system regulates many biological systems, and disruptions may result in
disorders, such as diabetes, thyroid dysfunction, Cushing's syndrome, and obesity. The total …

Down syndrome is the most common chromosomal abnormality diagnosed in newborn
babies. Infants with Down syndrome have characteristic dysmorphic features and can have …

People with Down syndrome (PWDS) are more at risk for developing obesity, oxidative
stress disorders, metabolic disorders, and lipid and carbohydrate profile disorders than the …

Osteoporosis is 1 of the common diseases of bone metabolism in clinic. With the aging of the
population in China, osteoporosis is becoming more and more serious, and it has become 1 …

Studies regarding cardiometabolic risk (CMR) for individuals with Down syndrome (DS)
conflict. Our previous research in youth with DS, aged 10–20 years, found increased …

Background The life expectancy of individuals with trisomy 21 (Down syndrome, DS) has
risen to more than 60 years over the past few decades. As a result, diseases arising in mid …

We aim to overview Addison's disease (AD) with regard to current diagnosis and
management. This is a narrative review of full-length articles published in English between …

Down syndrome develops due to the presence of supernumerary chromosome 21. This
diagnosis is made in approximately 1: 800 live births. The tendency to develop autoimmune …