Curative cancer therapy remains a major challenge particularly in cancers displaying
multidrug resistance (MDR). The MDR phenotype is characterized by cross-resistance to a …

Despite an increasing arsenal of anticancer therapies, many patients continue to have poor
outcomes due to the therapeutic failures and tumor relapses. Indeed, the clinical efficacy of …

Low-molecular-weight biothiols such as homocysteine, cysteine, and glutathione are
metabolites of the sulfur cycle and play important roles in biological processes such as the …

Protein phosphatase–2A (PP2A) is a primary serine–threonine phosphatase that modulates
inflammatory responses in asthma and chronic obstructive pulmonary disease (COPD) …

Acute lymphoblastic leukemia (ALL) is one of the most common hematological malignancies
at pediatric ages and is characterized by different chromosomal rearrangements and genetic …

Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL) is one of the more
common forms of B cell malignancy. Although the condition has a variable clinical course …

Measurement of chiral thiol compounds such as glutathione (GSH), cysteine (Cys), and
homocysteine (Hcy) in human serum plays an important role in the early diagnosis and …

The aim of the present study was to evaluate in patients with acute lymphoblastic leukemia
(ALL), the oxidative status and antioxidant defense and its involvement in the relapse of ALL …

Oxidative stress has been implicated in the development of several types of cancer,
including myelodysplastic syndromes (MDS), as well as in the resistance to treatment. In this …

This study evaluated the activity of superoxide dismutase (SOD1), glutathione reductase
(GR) and total antioxidant status (TAS) in the hemolysate and sera of patients with acute …