[HTML][HTML] Chronic pain after spine surgery: Insights into pathogenesis, new treatment, and preventive therapy
Chronic pain after spine surgery (CPSS) is often characterized by intractable low back pain
and/or radiating leg pain, and has been reported in 8–40% of patients that received lumbar …
and/or radiating leg pain, and has been reported in 8–40% of patients that received lumbar …
The PATIENT Approach: A New Bundle for the Management of Chronic Pain
P Buonanno, A Marra, C Iacovazzo, M Vargas… - Journal of Personalized …, 2023 - mdpi.com
Background: Chronic pain is one of the most challenging diseases for physicians as its
etiology and manifestations can be extremely varied. Many guidelines have been published …
etiology and manifestations can be extremely varied. Many guidelines have been published …
High-frequency electrical stimulation attenuates neuronal release of inflammatory mediators and ameliorates neuropathic pain
H Yang, T Datta-Chaudhuri, SJ George, B Haider… - Bioelectronic …, 2022 - Springer
Background Neuroinflammation is an important driver of acute and chronic pain states.
Therefore, targeting molecular mediators of neuroinflammation may present an opportunity …
Therefore, targeting molecular mediators of neuroinflammation may present an opportunity …
[HTML][HTML] Development and validation of a nomogram to predict chronic postoperative pain in elderly orthopedic patients
X Liu, N Li, Y Gao, L Yin, T Zhang… - Annals of Palliative …, 2021 - apm.amegroups.org
Background: At present, there is no nomogram for predicting chronic postoperative pain
(CPSP) in elderly orthopedic patients. This study aimed to develop and validate a predictive …
(CPSP) in elderly orthopedic patients. This study aimed to develop and validate a predictive …
Advances in Spinal Cord Neuromodulation: The Integration of Neuroengineering, Computational Approaches, and Innovative Conceptual Frameworks
PF Pradat, D Hayon, S Blancho, P Neveu… - Journal of personalized …, 2023 - mdpi.com
Spinal cord stimulation (SCS) is an approved treatment for intractable pain and has recently
emerged as a promising area of research for restoring function after spinal cord lesion. This …
emerged as a promising area of research for restoring function after spinal cord lesion. This …
Spinal cord stimulation combined with exercise in patients diagnosed with persistent spinal pain syndrome. Study protocol for a randomized control trial
J Vicente-Mampel, F Falaguera-Vera… - Plos one, 2024 - journals.plos.org
Introduction Administration of spinal cord stimulation to individuals with PSPS-T1/2 may
induce supraspinal descending activation. Similarly, exercise is recognized as a …
induce supraspinal descending activation. Similarly, exercise is recognized as a …
Management of refractory cancer pain with intrathecal drug delivery and spinal cord stimulation
E Bulat, JE Crowther, V Chakravarthy… - Palliative Medicine …, 2024 - liebertpub.com
Background: Intrathecal pumps (ITPs) are indicated for refractory cancer pain and decrease
systemic opioid requirements. While not yet indicated for cancer pain, spinal cord stimulators …
systemic opioid requirements. While not yet indicated for cancer pain, spinal cord stimulators …
Identification and analysis of immunogenicity and immunotherapy efficacy by fatty acid genes: a novel prognostic features of lumbar disc herniation and Mendelian …
Q Shang, W Xiang, Y Wu, Y Lu, Z Li… - International Journal …, 2024 - Taylor & Francis
Background: Sciatica is a phrase used to describe radiating leg discomfort. The most
common cause is lumbar disc herniation (LDH), which is considered to start in the nucleus …
common cause is lumbar disc herniation (LDH), which is considered to start in the nucleus …