Methotrexate (MTX) is a cytotoxic chemotherapeutic agent used for treatment of several
cancers. Nephrotoxicity, an adverse side effect of high-dose MTX, is attributed to abnormal …

The effects of montelukast against methotrexate‐induced liver damage were investigated.
35 Wistar albino female rats were divided into 5 groups as follows: group I: control; group II …

Cysteinyl leukotrienes released by mast cells trigger the symptoms of asthma, including
bronchoconstriction and vasoconstriction. Therefore, effective leukotriene inhibitors were …

Methods: The authors conducted a scoping review using PubMed, Scopus, and Web of
Science databases to identify relevant studies investigating the impact of montelukast on …

This study aimed to investigate the possible protective effect of paricalcitol on experimental
amikacin-induced nephrotoxicity model in rats. Wistar albino rats (n= 32) were allocated into …

Materials and Methods: Thirty-five Wistar albino female rats were randomly divided into 5
groups as follows: Group I: Control; Group II: Control+ ML; Group III: DOX; Group IV: DOX+ …

Background Amikacin has the largest spectrum among aminoglycosides, its nephrotoxic
effect limits its utilization. Our purpose in this study is to review the protective effect of …

Background The underlying mechanisms of nephrotic syndrome (NS) are still under debate
and the need for more effective and less toxic treatment is challenging. We aimed to …

Background: Diabetic nephropathy is a progressive condition and a leading cause of end-
stage renal disease. Oxidative stress and inflammation play an important role in its …

Background Doxorubicin is a potent chemotherapy agent used to treat a broad spectrum of
malignancies, but it has a significant nephrotoxicity which associated with increase …