Design and translation of injectable biomaterials
Injectable biomaterials, including bulk materials and particulate materials, can be delivered
in a minimally invasive way and may provide alternative treatment options for conditions that …
in a minimally invasive way and may provide alternative treatment options for conditions that …
Regenerative Medicine in Urogynecology: Where We Are and Where We Want to Be
T Henderson, KL Christman, M Alperin - Urogynecology, 2024 - journals.lww.com
Pelvic floor disorders (PFDs) constitute a major public health issue given their negative
effect on quality of life for millions of women worldwide and the associated economic …
effect on quality of life for millions of women worldwide and the associated economic …
Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives
W Luo, L Ren, B Hu, H Zhang, Z Yang, L Jin… - Advanced …, 2025 - Wiley Online Library
Fibrous hydrogels (FGs), characterized by a 3D network structure made from prefabricated
fibers, fibrils and polymeric materials, have emerged as significant materials in numerous …
fibers, fibrils and polymeric materials, have emerged as significant materials in numerous …
Tracking of Nascent Matrix Deposition during Muscle Stem Cell Activation across Lifespan Using Engineered Hydrogels
Adult stem cells occupy a niche that contributes to their function, but how stem cells rebuild
their microenvironment after injury remains an open‐ended question. Herein, biomaterial …
their microenvironment after injury remains an open‐ended question. Herein, biomaterial …
Long-term health outcomes and quality of life in women with untreated pelvic floor dysfunction: a single-center cohort study
W Chen, J Gong, M Liu, YC Cai - Frontiers in Public Health, 2025 - frontiersin.org
Objective This study aimed to evaluate the long-term health outcomes and quality of life
(HRQoL) associated with untreated pelvic floor dysfunction (PFD) in women, and to identify …
(HRQoL) associated with untreated pelvic floor dysfunction (PFD) in women, and to identify …
Beyond Traditional Medicine: EVs-Loaded Hydrogels as a Game Changer in Disease Therapeutics
Extracellular vesicles (EVs), especially exosomes, have shown great therapeutic potential in
the treatment of diseases, as they can target cells or tissues. However, the therapeutic effect …
the treatment of diseases, as they can target cells or tissues. However, the therapeutic effect …
Shift from Pro-to Anti-Inflammatory Phase in Pelvic Floor Muscles at Postpartum Matches Histological Signs of Regeneration in Multiparous Rabbits
E Rodríguez-Benítez, K López-García, N Xelhuantzi… - Medicina, 2024 - mdpi.com
Background and Objectives: Pelvic floor muscles (PFM) play a core role in defecation and
micturition. Weakening of PFM underlies urogynecological disorders such as pelvic organ …
micturition. Weakening of PFM underlies urogynecological disorders such as pelvic organ …
Repeated birth injuries lead to long-term pelvic floor muscle dysfunction in the preclinical rat model
Background Vaginal childbirth is a key risk factor for pelvic floor muscle injury and
dysfunction, and subsequent pelvic floor disorders. Multiparity further exacerbates these …
dysfunction, and subsequent pelvic floor disorders. Multiparity further exacerbates these …
Mechanical Stress-Oxidative Stress Axis: Biological Basis in the Vaginal Wall and Pelvic Floor Muscles of Rats with Simulated Birth Injury
Q Wang, X Wu, S Wang, B Xie, X Sun… - International …, 2024 - Springer
Abstract Introduction and Hypothesis Vaginal delivery and resulting pelvic floor muscle
(PFM) dysfunction are significant risk factors for pelvic floor dysfunction (PFD). Despite this …
(PFM) dysfunction are significant risk factors for pelvic floor dysfunction (PFD). Despite this …
[HTML][HTML] Quantification of local matrix deposition during muscle stem cell activation using engineered hydrogels
Adult stem cells occupy a niche that contributes to their function, but how stem cells remodel
their microenvironment remains an open-ended question. Herein, biomaterials-based …
their microenvironment remains an open-ended question. Herein, biomaterials-based …