Biomaterials and advanced technologies for hemostatic management of bleeding

DSA Hickman, CL Pawlowski, UDS Sekhon… - Advanced …, 2018 - Wiley Online Library
Bleeding complications arising from trauma, surgery, and as congenital, disease‐
associated, or drug‐induced blood disorders can cause significant morbidities and …

Hemostatic biomaterials to halt non-compressible hemorrhage

S Jiang, S Liu, S Lau, J Li - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Non-compressible hemorrhage is an unmet clinical challenge, which occurs in inaccessible
sites in the body where compression cannot be applied to stop bleeding. Current treatments …

Degradable gelatin-based IPN cryogel hemostat for rapidly stopping deep noncompressible hemorrhage and simultaneously improving wound healing

Y Huang, X Zhao, Z Zhang, Y Liang, Z Yin… - Chemistry of …, 2020 - ACS Publications
Biodegradable cryogel wound dressing which can stop deep noncompressible hemorrhage
and simultaneously promote wound healing is a highly promising biomaterial in clinics …

Injectable dry cryogels with excellent blood-sucking expansion and blood clotting to cease hemorrhage for lethal deep-wounds, coagulopathy and tissue regeneration

X Zhao, Y Liang, B Guo, Z Yin, D Zhu, Y Han - Chemical Engineering …, 2021 - Elsevier
Designing expandable dry cryogels with biodegradability, rapid blood-sucking expansion
and hemostasis for lethal non-compressible hemorrhage and coagulopathy hemorrhage still …

Chitosan/alginate/hyaluronic acid polyelectrolyte composite sponges crosslinked with genipin for wound dressing application

X Meng, Y Lu, Y Gao, S Cheng, F Tian, Y Xiao… - International Journal of …, 2021 - Elsevier
Wound dressing composed of polyelectrolyte complexes (PECs), based on
chitosan/alginate/hyaluronic acid (CS/ALG/HYA) crosslinked by genipin, was prepared by …

A shape memory foam composite with enhanced fluid uptake and bactericidal properties as a hemostatic agent

TL Landsman, T Touchet, SM Hasan, C Smith… - Acta biomaterialia, 2017 - Elsevier
Uncontrolled hemorrhage accounts for more than 30% of trauma deaths worldwide. Current
hemostatic devices focus primarily on time to hemostasis, but prevention of bacterial …

Emerging innovative wound dressings

ME Aljghami, S Saboor, S Amini-Nik - Annals of biomedical engineering, 2019 - Springer
The skin provides a protective barrier to the body against the environment. Ineffective
healing of damaged skin can cause a chronic wound which would increase the risk of …

[HTML][HTML] Prehospital control of life-threatening truncal and junctional haemorrhage is the ultimate challenge in optimizing trauma care; a review of treatment options …

SE Van Oostendorp, E Tan, LMG Geeraedts - Scandinavian journal of …, 2016 - Springer
Introduction Exsanguination following trauma is potentially preventable. Extremity
tourniquets have been successfully implemented in military and civilian prehospital care …

Peptide-immobilized starch/PEG sponge with rapid shape recovery and dual-function for both uncontrolled and noncompressible hemorrhage

X Yang, W Liu, Y Shi, G Xi, M Wang, B Liang, Y Feng… - Acta Biomaterialia, 2019 - Elsevier
It is challenging for traditional hemostatic sponges to meet the clinic demand for both
uncontrolled and noncompressible hemorrhage. With the aim to develop a rapid shape …

Hemostatic shape memory polymer foams with improved survival in a lethal traumatic hemorrhage model

HT Beaman, E Shepherd, J Satalin, S Blair… - Acta Biomaterialia, 2022 - Elsevier
Although there are many hemostatic agents available for use on the battlefield, uncontrolled
hemorrhage is still the primary cause of preventable death. Current hemostatic dressings …