A spinal cord injury disrupts communication between the brain and the circuits in the spinal
cord that regulate neurological functions. The consequences are permanent paralysis, loss …

Magnetic resonance imaging and spectroscopic techniques are widely used in humans both
for clinical diagnostic applications and in basic research areas such as cognitive …

Electrical activity in neurons requires a seamless functional coupling between
plasmalemmal ion channels and ion transporters. Although ion channels have been studied …

Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Many human spinal cord injuries are anatomically incomplete but exhibit complete paralysis.
It is unknown why spared axons fail to mediate functional recovery in these cases. To …

Neurotrophins are a family of proteins that regulate neuronal survival, synaptic function, and
neurotransmitter release, and elicit the plasticity and growth of axons within the adult central …

We report that the oxytocin-mediated neuroprotective γ-aminobutyric acid (GABA) excitatory-
inhibitory shift during delivery is abolished in the valproate and fragile X rodent models of …

Ionic currents and the network-driven patterns they generate differ in immature and adult
neurons: The developing brain is not a “small adult brain.” One of the most investigated …

A major unresolved issue in treating pain is the paradoxical hyperalgesia produced by the
gold-standard analgesic morphine and other opiates. We found that hyperalgesia-inducing …

Transplantation of human mesenchymal stem cells has been shown to reduce infarct size
and improve functional outcome in animal models of stroke. Here, we report a study …