Exosomes are nanovesicles with different contents that play a role in various biological and
pathological processes. It offers significant advantages over other delivery systems such as …

Osteoporosis is a systemic metabolic bone disease with characteristics of bone loss and
microstructural degeneration. The personal and societal costs of osteoporosis are …

Nanocarriers as drug/biomolecule delivery systems have been significantly developed
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …

Background Osteoarthritis (OA) is the most common joint disease worldwide. In the past
decade, mesenchymal stem cells (MSCs) have been used widely for the treatment of OA. A …

Tissue regeneration by stem cells is driven by the paracrine activity of shedding vesicles and
exosomes, which deliver specific cargoes to the recipient cells. Proteins, RNA, cytokines and …

Abstract Exosomes, 60–200-nm extracellular vesicles secreted from cells, have been used
as an active pharmaceutical ingredient or drug carrier in disease treatment. Human-and …

The recent advances in translational and nanomedicine have paved the way for developing
the targeted drug delivery system at a greater pace among global researchers. On par with …

Drug delivery to the central nervous system (CNS) is limited due to the presence of the blood–
brain barrier (BBB), a selective physiological barrier located at the brain microvessels that …

Background Platelet-rich plasma (PRP) provides a nonsurgical approach for treating
osteoarthritis (OA). Exosomes that play vital roles in intercellular communication have been …

The pathogenesis of osteoarthritis (OA) is poorly understood, and therapeutic approaches
are limited to preventing progression of the disease. Recent studies have shown that …