In the last 2 decades, lipidomics has become one of the fastest expanding scientific disciplines in biomedical research. With an increasing number of new research groups to …
Metabolomics has evolved as a discipline from a discovery and functional genomics tool, and is now a cornerstone in the era of big data-driven precision medicine. Sample …
B Peng, D Kopczynski, BS Pratt, CS Ejsing… - Nature …, 2020 - nature.com
Mass spectrometry (MS)-based targeted lipidomics enables the robust quantification of selected lipids under various biological conditions but comprehensive software tools to …
S Heuckeroth, A Behrens, C Wolf, A Fütterer… - Nature …, 2023 - nature.com
Trapped ion mobility spectrometry (TIMS) adds an additional separation dimension to mass spectrometry (MS) imaging, however, the lack of fragmentation spectra (MS2) impedes …
MC Manke, R Ahrends, O Borst - Pharmacology & Therapeutics, 2022 - Elsevier
The function of platelets–and thereby the balance between thrombosis and hemostasis– critically depends on their lipid composition. At the same time, platelets are capable of …
D Kopczynski, CS Ejsing, JG McDonald, T Bamba… - Journal of lipid …, 2024 - jlr.org
The rapid increase in lipidomic studies has led to a collaborative effort within the community to establish standards and criteria for producing, documenting, and disseminating data …
J Koch, K Watschinger, ER Werner… - Frontiers in Cell and …, 2022 - frontiersin.org
Typically, glycerophospholipids are represented with two esterified fatty acids. However, by up to 20%, a significant proportion of this lipid class carries an ether-linked fatty alcohol side …
Nanoscale separation techniques (Capillary/nano-LC, CE, CEC and Chip based LC/CE/CEC) present a prospective trend in modern analytical chemistry due to allowing …
NR Zhang, NG Hatcher, K Ekroos, K Kedia… - Journal of Lipid …, 2022 - ASBMB
A major challenge of lipidomics is to determine and quantify the precise content of complex lipidomes to the exact lipid molecular species. Often, multiple methods are needed to …