Protozoan diseases continue to be a worldwide social and economic health problem.
Increased drug resistance, emerging cross resistance, and lack of new drugs with novel …

In global health, critical challenges have arisen from infectious diseases, including the
emergence and reemergence of old and new infectious diseases. Emergence and …

African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense,
and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and …

Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African
Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same …

Summary Background Human African trypanosomiasis caused by Trypanosoma brucei
gambiense (gambiense HAT) in patients with late-stage disease requires hospital admission …

Human trypanosomiasis and leishmaniasis are vector‐borne neglected tropical diseases
caused by infection with the protozoan parasites Trypanosoma spp. and Leishmania spp …

Abstract Replication Protein A (RPA) is a broadly conserved complex comprised of the
RPA1, 2 and 3 subunits. RPA protects the exposed single-stranded DNA (ssDNA) during …

Parasitic protozoan diseases continue to rank among the world's greatest global health
problems, which are also common among poor populations. Currently available drugs for …

The diseases caused by African trypanosomes (AT) are of both medical and veterinary
importance and have adversely influenced the economic development of sub-Saharan …

Human African trypanosomiasis (HAT) is responsible for around 3000 reported cases each
year. Treatments for HAT are expensive and problematic to administer, and available drugs …