Bifunctional stapled polypeptides and uses thereof

GL Verdine, TN Grossmann, RE Moellering… - US Patent …, 2015 - Google Patents
2010-11-15 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …

Stabilized alpha helical peptides and uses thereof

LD Walensky, SJ Korsmeyer, GL Verdine - US Patent 8,796,418, 2014 - Google Patents
Novel polypeptides and methods of making and using the same are described herein. The
polypeptides include cross linking (“hydrocarbon stapling”) moieties to provide a tether …

Stabilized alpha helical peptides and uses thereof

LD Walensky, SJ Korsmeyer, G Verdine - US Patent 8,198,405, 2012 - Google Patents
US8198405B2 - Stabilized alpha helical peptides and uses thereof - Google Patents
US8198405B2 - Stabilized alpha helical peptides and uses thereof - Google Patents Stabilized …

Biologically active peptidomimetic macrocycles

HM Nash, R Kapeller-Libermann… - US Patent App. 12 …, 2009 - Google Patents
The present invention provides biologically active peptidomimetic macrocycles with
improved properties rela tive to a corresponding crosslinked polypeptide. 0004. In one …

Stitched polypeptides

GL Verdine, YW Kim - US Patent 8,592,377, 2013 - Google Patents
2008-08-27 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …

Stabilized p53 peptides and uses thereof

F Bernal, LD Walensky, GL Verdine… - US Patent …, 2014 - Google Patents
US8889632B2 - Stabilized p53 peptides and uses thereof - Google Patents US8889632B2 -
Stabilized p53 peptides and uses thereof - Google Patents Stabilized p53 peptides and uses …

Methods for preparing purified polypeptide compositions

HM Nash, M Iadanza, C Leitheiser… - US Patent …, 2015 - Google Patents
US9206223B2 - Methods for preparing purified polypeptide compositions - Google Patents
US9206223B2 - Methods for preparing purified polypeptide compositions - Google Patents …

Biologically Active Peptidomimetic Macrocycles

HM Nash, R Kapeller-Libermann… - US Patent App. 12 …, 2011 - Google Patents
2010-06-11 Assigned to AILERON THERAPEUTICS, INC. reassignment AILERON
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Stabilized alpha helical peptides and uses thereof

LD Walensky, SJ Korsmeyer, G Verdine - US Patent 9,273,099, 2016 - Google Patents
Novel polypeptides and methods of making and using the same are described herein. The
polypeptides include cross linking (“hydrocarbon stapling) moieties to provide a tether …

Stabilized alpha helical peptides and uses thereof

LD Walensky, SJ Korsmeyer, G Verdine - US Patent 9,464,115, 2016 - Google Patents
Related US Application Data (63) Continuation of application No. 13/252,751, filed on Oct. 4,
2011, now Pat. No. 9,273,099, which is a continuation of application No. 12/233,555, filed on …