Streptomycetes are the most abundant source of antibiotics. Typically, each species
produces several antibiotics, with the profile being species specific. Streptomyces coelicolor …

Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …

Covering: up to 2015 In recent years, bacterial interspecies interactions mediated by small
molecule natural products have been found to give rise to a surprising array of phenotypes …

Actinomycetes are a rich source of natural products, and these mycelial bacteria produce the
majority of the known antibiotics. The increasing difficulty to find new drugs via high …

While soil‐dwelling actinomycetes are renowned for secreting natural products, little is
known about the roles of these molecules in mediating actinomycete interactions. In a …

Streptomyces antibiotic regulatory protein (SARP) family regulators are well-known
activators of antibiotic biosynthesis in streptomycetes. The respective genes occur in various …

Microbes are remarkably social. They live in complex, interdependent communities where
they share and exchange a variety of beneficial compounds ranging from cell− cell signals …

Actinomycetes are soil-dwelling Gram-positive bacteria, industrially relevant as producers of
a wide range of bioactive secondary metabolites, including many antibiotics of clinical and …

Actinobacteria are a large and diverse group of bacteria that are known to produce a wide
range of secondary metabolites, many of which have important biological activities …

Few studies were reported about the regulatory mechanism of lincomycin biosynthesis since
it was found in 1962. Although we have proved that a cluster-situated regulator (CSR) LmbU …