Salivary biomarkers: toward future clinical and diagnostic utilities

JM Yoshizawa, CA Schafer, JJ Schafer… - Clinical microbiology …, 2013 - Am Soc Microbiol
The pursuit of timely, cost-effective, accurate, and noninvasive diagnostic methodologies is
an endeavor of urgency among clinicians and scientists alike. Detecting pathologies at their …

[HTML][HTML] Resident viruses and their interactions with the immune system

BA Duerkop, LV Hooper - Nature immunology, 2013 - nature.com
The human body is colonized with a diverse resident microflora that includes viruses.
Recent studies of metagenomes have begun to characterize the composition of the …

[HTML][HTML] Enteric viruses ameliorate gut inflammation via toll-like receptor 3 and toll-like receptor 7-mediated interferon-β production

JY Yang, MS Kim, E Kim, JH Cheon, YS Lee, Y Kim… - Immunity, 2016 - cell.com
Metagenomic studies show that diverse resident viruses inhabit the healthy gut; however,
little is known about the role of these viruses in the maintenance of gut homeostasis. We …

Characterization of the salivary microbiome in patients with pancreatic cancer

PJ Torres, EM Fletcher, SM Gibbons, M Bouvet… - PeerJ, 2015 - peerj.com
Clinical manifestations of pancreatic cancer often do not occur until the cancer has
undergone metastasis, resulting in a very low survival rate. In this study, we investigated …

Microbial community profiling of human saliva using shotgun metagenomic sequencing

NA Hasan, BA Young, AT Minard-Smith, K Saeed… - PLoS …, 2014 - journals.plos.org
Human saliva is clinically informative of both oral and general health. Since next generation
shotgun sequencing (NGS) is now widely used to identify and quantify bacteria, we …

[HTML][HTML] A method for selectively enriching microbial DNA from contaminating vertebrate host DNA

GR Feehery, E Yigit, SO Oyola, BW Langhorst… - PloS one, 2013 - journals.plos.org
DNA samples derived from vertebrate skin, bodily cavities and body fluids contain both host
and microbial DNA; the latter often present as a minor component. Consequently, DNA …

A systematic review of the root canal microbiota associated with apical periodontitis: lessons from next‐generation sequencing

D Manoil, K Al‐Manei… - PROTEOMICS–Clinical …, 2020 - Wiley Online Library
Next‐generation sequencing (NGS) has now been applied for a decade to characterize the
microbiota composition of infected dental root canals associated with apical periodontitis …

Old age and other factors associated with salivary microbiome variation

JL Schwartz, N Peña, N Kawar, A Zhang, N Callahan… - BMC Oral Health, 2021 - Springer
Background Many factors can contribute to the exact makeup of the salivary microbiome.
Differences in the oral microbiome occur with old age, which may be due to oral conditions …

Human virome

S Zárate, B Taboada, M Yocupicio-Monroy… - Archives of Medical …, 2017 - Elsevier
The human virome is composed by the set of all viruses, eukaryotic and prokaryotic, present
in the human body; as each body compartment constitutes a different microenvironment, the …

Saliva: a fluid of study for OMICS

B Cuevas-Córdoba… - Omics: a journal of …, 2014 - liebertpub.com
Saliva is a fluid that can be collected easily and noninvasively. Its functions in the oral cavity
are well known. Advances in molecular biology and technology, as well as research …