Methylenetetrahydrofolate reductase (MTHFR) is essential for DNA biosynthesis and the
epigentic process of DNA methylation. It has been reported that abnormal DNA methylation …

Animal models have shown evidence of the role of maternal methyl donor status and its
metabolism (one-carbon metabolism) in normal embryonic maxillofacial development …

Introducción El padecimiento de labio paladar hendido es una de las alteraciones
congénitas más comunes que afecta las estructuras de la cara. El objetivo de este trabajo …

The aim of the study was to investigate the association between environmental factors and
nonsyndromic cleft of the lip and/or palate (NSCL/P) in Yantai District, China. A retrospective …

Background Oral clefts are among the most common congenital anomalies. Most studies on
risk factors of oral clefts have been carried out in developed countries. We investigated the …

Objective To study the relationship between environmental factors and nonsyndromic cleft of
the lip and/or palate (NSCLP) in eastern Guangdong for the prevention of NSCLP. Methods …

Objective Several studies have reported the association between methylenetetrahydrofolate
reductase (MTHFR) C677T and A1298C polymorphisms and nonsyndromic cleft lip with or …

Background This study was conducted to estimate the precise association of fetal MTHFR
677 C> T polymorphism with risk of nonsyndromic cleft lip with or without cleft palate …

Objective: To identify and review published data on the risks associated with cleft lip and/or
palate (CL/P) in lower-middle-income countries (LMICs). Design: A systematic review of …

Objective: To evaluate the association between polymorphism of reduced folate carrier 1
(RFC1) A80 G in infants and the risk of non-syndromic cleft lip/palate (NSCL/P), in a meta …