Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a global pandemic with …

Phospholipase D (PLD) is an enzyme that catalyzes the hydrolysis of phosphatidylcholine
into phosphatidic acid and free choline. In mammals, PLD exists in two well-characterized …

Monocytes can develop an exhausted memory state characterized by reduced
differentiation, pathogenic inflammation, and immune suppression that drives immune …

Abstract Phospholipase D (PLD) isoforms PLD1 and PLD2 serve as the primary nodes
where diverse signaling pathways converge. However, their isoform‐specific functions …

Background Increased inflammatory exudation caused by endothelium and endothelial
junction damage is a typical pathological feature of acute respiratory distress …

Sepsis and sepsis‐associated lung inflammation significantly contribute to the morbidity and
mortality of critical illness. Here, we examined the hypothesis that neuronal guidance …

Idiopathic pulmonary fibrosis (IPF) is a pernicious lung disease characterized by alveolar
epithelial apoptosis, dysregulated repair of epithelial injury, scar formation, and respiratory …

Introduction With the mounting number of cancer survivors, the complications following
cancer treatment become novel conundrums and starve for countermeasures. Intravenous …

Increased permeability of vascular lung tissues is a hallmark of acute lung injury and is often
caused by edemagenic insults resulting in inflammation. Vascular endothelial (VE)-cadherin …

Background Acute pancreatitis (AP) is an inflammatory process unexpectedly occurring in
the pancreas, imposing a substantial burden on healthcare systems. Herein, we aimed to …