Interleukin 37 limits monosodium urate crystal-induced innate immune responses in human and murine models of gout

L Liu, Y Xue, Y Zhu, D Xuan, X Yang, M Liang… - Arthritis research & …, 2016 - Springer
Abstract Background Interleukin (IL)-37 has emerged as a fundamental inhibitor of innate
immunity. Acute gout is a self-limiting inflammatory response to monosodium urate (MSU) …

Identification of inflammation-related biomarker Pro-ADM for male patients with gout by comprehensive analysis

K Qiu, T Zeng, Y Liao, J Min, N Zhang, M Peng… - Frontiers in …, 2022 - frontiersin.org
Objective Gout is a local inflammatory disease caused by the deposition of monosodium
urate (MSU) crystals in joints or adjacent tissues. When some gout occurs without …

Could microRNAs be regulators of gout pathogenesis?

Y Wang, D Xu, B Wang, X Hou - Cellular Physiology and Biochemistry, 2015 - karger.com
MicroRNAs (miRNAs) are a class of noncoding RNAs that mainly negatively regulate gene
expression. miRNAs have important roles in many diseases, including inflammatory …

Citrullination of epithelial neutrophil–activating peptide 78/CXCL5 results in conversion from a non–monocyte‐recruiting chemokine to a monocyte‐recruiting …

K Yoshida, O Korchynskyi, PP Tak… - Arthritis & …, 2014 - Wiley Online Library
Objective To examine whether the citrullinated chemokines epithelial neutrophil–activating
peptide 78 (ENA‐78)/CXCL5, macrophage inflammatory protein 1α/CCL3, and monocyte …

Altered distribution and enhanced osteoclastogenesis of mucosal-associated invariant T cells in gouty arthritis

YN Cho, HS Jeong, KJ Park, HS Kim, EH Kim… - …, 2020 - academic.oup.com
Objective This study was designed to investigate the role of mucosal-associated invariant T
(MAIT) cells in gouty arthritis (GA) and their effects on osteoclastogenesis. Methods Patients …

Suppression of NF-κB reduces myocardial no-reflow

M Zeng, H Yan, Y Chen, H Zhao, Y Lv, C Liu, P Zhou… - 2012 - journals.plos.org
No-reflow phenomenon is a risk factor which severely compromises the benefits of coronary
revascularization in patients with acute myocardial infarction. Inflammatory response, as an …

[HTML][HTML] CXCR1/CXCR2 antagonist G31P inhibits nephritis in a mouse model of uric acid nephropathy

Y Ye, Y Zhang, B Wang, W Walana, J Wei… - Biomedicine & …, 2018 - Elsevier
The prevalence of gout is relatively high worldwide, and many gout patients suffer from uric
acid nephropathy (UAN) concomitantly. ELR-CXC chemokines such as CXCL8 and CXCL1 …

Significance of Serum Markers and Urinary Microalbumin in the Diagnosis of Early Renal Damage in Patients with Gout.

H Tang, Y Zhao, C Tan, Y Liu - Clinical Laboratory, 2021 - search.ebscohost.com
Background: To explore the diagnostic value of changes in serum CXC Motif Chemokine
Ligand 16 (CXCL16), cystatin C (CysC), cyclooxygenase-2 (COX-2), and urinary …

Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis

G Edhayan, RA Ohara, WA Stinson, MA Amin… - Arthritis research & …, 2016 - Springer
Background Inhibitor of DNA binding 1 (Id1) is a nuclear protein containing a basic helix-
loop-helix (bHLH) domain that regulates cell growth by selective binding and prevention of …

Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts

PS Tsou, B Balogh, AJ Pinney, G Zakhem… - Arthritis research & …, 2014 - Springer
Abstract Introduction Systemic sclerosis (SSc) is a connective tissue disease characterized
by fibrosis of the skin and organs. Increase in oxidative stress and platelet-derived growth …